20034-54-2

Basic information

• Product Name: 2H-1,2,3-Triazole, 4-(4-bromophenyl)-2-phenyl-
• CAS NO: 20034-54-2
• Molecular Formula: C14H10BrN3
• Molecular Weight: 300.157
• Mol File: 20034-54-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2H-1,2,3-Triazole, 4-(4-bromophenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2,3-Triazole, 4-(4-bromophenyl)-2-phenyl-(20034-54-2)
• EPA Substance Registry System: 2H-1,2,3-Triazole, 4-(4-bromophenyl)-2-phenyl-(20034-54-2)

Safety Data

• Hazardous Substances Data: 20034-54-2(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 13195-79-4 2,2-dibromo-1-(4-bromophenyl)ethan-1-one 
• 100-63-0 phenylhydrazine 
• 99-73-0 para-bromophenacyl bromide 
• 3343-45-1 4-bromo-2-hydroxyacetophenone 
• 7644-04-4 4-bromophenacylamine 

Relevant articles and documents

A novel and efficient strategy for the preparation of 2,4-disubstituted-1,2,3-triazoles

We have developed a novel and efficient method for the preparation of 2,4-disubstituted-1,2,3-triazoles. These compounds 3a-3p were synthesized in good yield by refluxing α-aminoacetophenones and hydrazines in glacial acetic acid. The reaction proceeds under mild conditions and is compatible with various functional groups.

α,α-dibromoketones as useful precursors in organic synthesis: A simple and efficient synthesis of 2,4-diaryl- 1,2,3-triazoles via oxidative cyclization of bisphenylhydrazones

α,α-Dibromoacetophenones (1a-1f) on reaction with phenylhydrazine afford corresponding arylglyoxal bisphenylhydrazones (2a-2f). The oxidation of bishydrazones 2a-2f by using copper(II) chloride in acetic acid leads to intramolecular cyclization with the formation of 2,4-diaryl-1,2,3-triazoles (3a-3f). The method for the conversion 1 → 3 has been simplified by developing one-pot procedure without isolation of intermediates 2.