20764-35-6

Basic information

• Product Name: 1-(2-CHLORO-ETHOXY)-4-METHYL-BENZENE
• Synonyms: 1-(2-CHLORO-ETHOXY)-4-METHYL-BENZENE
• CAS NO: 20764-35-6
• Molecular Formula: C₉H₁₁ClO
• Molecular Weight: 170.64
• Mol File: 20764-35-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-CHLORO-ETHOXY)-4-METHYL-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-CHLORO-ETHOXY)-4-METHYL-BENZENE(20764-35-6)
• EPA Substance Registry System: 1-(2-CHLORO-ETHOXY)-4-METHYL-BENZENE(20764-35-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 20764-35-6(Hazardous Substances Data)

Usage

Description

1-(2-chloro-ethoxy)-4-methyl-benzene, also known as 4-methyl-1-(2-chloroethyl)benzene, is a chemical compound with the molecular formula C9H11ClO. It is a colorless liquid that is commonly used in the production of pharmaceuticals, agrochemicals, and dyes. This chemical compound is also utilized as a solvent in various industrial processes. It is important to handle 1-(2-chloro-ethoxy)-4-methyl-benzene with caution as it can be harmful if ingested or inhaled, and can cause irritation to the skin and eyes. Additionally, it should be stored in a cool, well-ventilated area away from heat and sources of ignition.

Uses

Used in Pharmaceutical Industry:
1-(2-chloro-ethoxy)-4-methyl-benzene is used as an intermediate for the synthesis of various pharmaceutical compounds. Its chemical structure allows for the creation of a wide range of drugs with different therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(2-chloro-ethoxy)-4-methyl-benzene is used as a building block for the development of pesticides and other agricultural chemicals. Its versatility in chemical reactions makes it a valuable component in the formulation of these products.
Used in Dye Industry:
1-(2-chloro-ethoxy)-4-methyl-benzene is used as a starting material in the production of various dyes. Its unique chemical properties contribute to the development of dyes with specific color characteristics and stability.
Used as a Solvent in Industrial Processes:
Due to its solvent properties, 1-(2-chloro-ethoxy)-4-methyl-benzene is utilized in various industrial processes. It is particularly useful in applications where a non-reactive, colorless solvent is required for the dissolution of other chemicals or for carrying out specific chemical reactions.

Upstream product

• 106-44-5 p-cresol 
• 80-41-1 2-chloroethyl tosylate 
• 15149-10-7 2-(4-methylphenoxy)ethanol 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 106271-16-3 (2-tert-butyl-4-methyl-phenyl)-(2-chloro-ethyl)-ether 
• 100369-38-8 dimethyl-dithiocarbamic acid-(2-p-tolyloxy-ethyl ester) 
• 5409-80-3 (2-chloro-ethyl)-(2-chloromethyl-4-methyl-phenyl)-ether 
• 114276-03-8 4-phenyl-1-(2-p-tolyloxy-ethyl)-piperidine-4-carboxylic acid ethyl ester 
• 856375-28-5 2-[ethyl-(2-p-tolyloxy-ethyl)-amino]-ethanol 
• 1005-62-5 4-tolyl vinyl ether 
• 141649-78-7 2-(2-p-Tolyloxy-ethyl)-malonic acid diethyl ester 
• 124947-14-4 2-methylene-4-(4-methylphenoxy)butyric acid 
• 141649-79-8 ethyl 2-methylene-4-(4-methylphenoxy)butyrate 
• 124947-23-5 2-acetylthiomethyl-4-(4-methylphenoxy)butyric acid 
• 63917-95-3 ethyl-(2-chloro-ethyl)-(2-p-tolyloxy-ethyl)-amine; hydrochloride 
• 106739-10-0 (2-tert-butyl-6-chloromethyl-4-methyl-phenyl)-(2-chloro-ethyl)-ether 
• 114985-31-8 S-[2-(2-chloro-ethoxy)-5-methyl-benzyl]-isothiourea; hydrochloride 
• 831231-49-3 1-(2-amino-5-ethyl-6-methyl-pyrimidin-4-yl)-3-(2-p-tolyloxyethylsulfanyl)-1H-diazirine 

Relevant articles and documents

Structure-activity studies of 3-benzoylpropionic acid derivatives suppressing adjuvant arthritis

3-Benzoylpropionic acid derivatives possess an immunomodulative activity and suppress adjuvant arthritis. To understand how substituents affect the biological activity, the quantitative structure-activity relationships of 30 compounds were analyzed by the adaptive least-squares method. For the suppressing activity in rats, the electronic effects and the structural feature of the substituent on benzene ring were suggested to be important. To reinforce and confirm the correlation, 4 additional compounds of phenoxybutyric acid derivatives were synthesized and tested with the rat adjuvant-induced arthritis. These compounds were found to have potent suppressing activity.