212503-29-2

Basic information

• Product Name: 1-(2,6-difluorobenzyl)-2-{[(2,6-difluorobenzyl)oxy]methyl}-1H-benzimidazole
• Synonyms: 1H-benzimidazole, 2-[[(2,6-difluorophenyl)methoxy]methyl]-1-[(2,6-difluorophenyl)methyl]-
• CAS NO: 212503-29-2
• Molecular Formula: C₂₂H₁₆F₄N₂O
• Molecular Weight: 400.3689
• Mol File: 212503-29-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 514.9°C at 760 mmHg
• Flash Point: 265.2°C
• Density: 1.3g/cm³
• Vapor Pressure: 3.37E-10mmHg at 25°C
• Refractive Index: 1.578
• PKA: 4.08±0.10(Predicted)
• CAS DataBase Reference: 1-(2,6-difluorobenzyl)-2-{[(2,6-difluorobenzyl)oxy]methyl}-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-difluorobenzyl)-2-{[(2,6-difluorobenzyl)oxy]methyl}-1H-benzimidazole(212503-29-2)
• EPA Substance Registry System: 1-(2,6-difluorobenzyl)-2-{[(2,6-difluorobenzyl)oxy]methyl}-1H-benzimidazole(212503-29-2)

Safety Data

• Hazardous Substances Data: 212503-29-2(Hazardous Substances Data)

Upstream product

• 4856-97-7 2-(Hydroxymethyl)benzimidazole 
• 85118-00-9 2,6-Difluorobenzyl bromide 
• 95-54-5 1,2-diamino-benzene 

Relevant articles and documents

Substituted benzimidazoles, and methods of use thereof, for the inhibition of HIV reverse transcription and for the treatment of HIV infection

The present invention provides compositions and methods for the treatment of HIV infection. In particular, the present invention provides non-nucleoside inhibitors of reverse transcriptase (RT), as well as methods to treat HIV infection using these non-nucleoside inhibitors of RT. In preferred embodiments, the present invention provides a novel class of substituted benzimidazoles, effective in the inhibition of human immunodeficiency virus (HIV) RT.