213598-07-3

Basic information

• Product Name: 3-CHLORO-4-ISOPROPOXY-BENZOIC ACID
• Synonyms: 3-CHLORO-4-ISOPROPOXY-BENZOIC ACID
• CAS NO: 213598-07-3
• Molecular Formula: C₁₀H₁₁ClO₃
• Molecular Weight: 214.64554
• Mol File: 213598-07-3.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 322.9 °C at 760 mmHg
• Flash Point: 149.073 °C
• Appearance: /
• Density: 1.253 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-CHLORO-4-ISOPROPOXY-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4-ISOPROPOXY-BENZOIC ACID(213598-07-3)
• EPA Substance Registry System: 3-CHLORO-4-ISOPROPOXY-BENZOIC ACID(213598-07-3)

Safety Data

• Hazardous Substances Data: 213598-07-3(Hazardous Substances Data)

Usage

General Description

3-Chloro-4-isopropoxy-benzoic acid, also known as isopropoxychlorobenzoic acid, is a chemical compound with the molecular formula C10H11ClO3. It is a white to off-white crystalline powder that is commonly used in the production of pharmaceuticals, agrochemicals, and other organic compounds. This chemical is a derivative of benzoic acid, featuring a chlorine atom and an isopropoxy group attached to the benzene ring. It is often utilized as an intermediate in the synthesis of various bioactive molecules and pharmaceutical ingredients, making it an important building block in organic chemistry. Additionally, 3-chloro-4-isopropoxy-benzoic acid exhibits significant potential for further research and development in the pharmaceutical and chemical industries due to its versatile and valuable properties.

InChI:InChI=1/C10H11ClO3/c1-6(2)14-9-4-3-7(10(12)13)5-8(9)11/h3-6H,1-2H3,(H,12,13)

Upstream product

• 213598-06-2 methyl 3-chloro-4-isopropoxybenzoate 
• 13205-46-4 4-isopropoxybenzoic acid 
• 855198-17-3 3-chloro-4-isopropoxy-benzoic acid ethyl ester 
• 3964-57-6 methyl 4-hydroxy-3-chlorobenzoate 
• 67-63-0 isopropyl alcohol 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 122488-52-2 ethyl 4-isopropoxybenzoate 
• 3964-58-7 3-chloro-4-hydroxybenzoic acid 
• 1312008-54-0 1-methylethyl 3-chloro-4-[(1-methylethyl)oxy]benzoate 
• 75-26-3 isopropyl bromide 
• 117482-84-5 3-chloro-4-fluorobenzonitrile 
• 916596-04-8 3-chloro-4-isopropoxybenzonitrile 

Downstream Products

• 869566-16-5 pentafluorophenyl 3-chloro-4-[(1-methylethyl)oxy]benzoate 
• 678181-75-4 (3-chloro-4-isopropoxyphenyl)methanol 
• 1034188-28-7 [4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)phenyl]methanol 
• 1034687-08-5 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indol-1-yl]propanoic acid 
• 1034688-78-2 5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indole 
• 1072947-92-2 ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indazol-1-yl]propanoate 
• 1072947-91-1 ethyl 4-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indazol-1-yl]butanoate 
• 1072948-35-6 ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indazol-1-yl]-2,2-dimethylpropanoate 
• 1072947-58-0 ethyl 3-[5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indazol-1-yl]propanoate 
• 1072947-57-9 5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indazole 
• 213767-19-2 3-chloro-4-[(1-methylethyl)oxy]benzoyl chloride 
• 1165946-32-6 1,1-dimethylethyl 7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1-[3-(methyloxy)-3-oxopropyl]-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carboxylate 
• 1165946-42-8 1,1-dimethylethyl 7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate 
• 1167416-29-6 1,1-dimethylethyl 7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate 

Relevant articles and documents

S1P1 AGONIST AND APPLICATION THEREOF

The present invention relates to a class of tricyclic compounds and an application thereof as a sphingosine 1-phosphate type 1 (S1P1) receptor agonist. The invention specifically relates to a compound represented by formula (II), and a tautomer and pharmaceutically acceptable salt of same.

THIADIAZOLE MODULATORS OF S1P AND METHODS OF MAKING AND USING

The invention is directed to compounds of the formula: wherein each of the variables are defined herein, as well as methods of making and using the compounds as agonists of S1P1 and/or S1P5 for instance treating an autoimmune disease.

SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND COMBINATION THERAPY THEREWITH

Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided, including compounds which modulate subtype 1 of the S1P receptor, and methods of their therapeutic and/or prophylactic use in combination with at least one other medicament adapted for treatement of a malcondition for which activation of S1P1 is medically indicated, such as multiple sclerosis.