2137-18-0 Usage
Description
Gestonorone, a steroidal progestin, is a synthetic hormone with various physiological effects. It is characterized by its ability to influence the body's hormonal balance, leading to accelerated body weight gain and causing atrophy of reproductive organs such as the prostate, uterus, and seminal vesicles in rats. Additionally, it serves as an inhibitor of the reductive pathway of testosterone metabolism, making it a compound of interest in the field of endocrinology and reproductive health.
Uses
Used in Pharmaceutical Applications:
Gestonorone is used as a pharmaceutical agent for its progestational effects. It is particularly useful in managing hormonal imbalances and conditions related to the reproductive system. Its ability to cause atrophy of reproductive organs in rats suggests potential applications in the treatment of hormone-dependent conditions.
Used in Research and Development:
In the field of research, Gestonorone is used as a research compound for studying the effects of progestins on the body. Its role in inhibiting the reductive pathway of testosterone metabolism makes it a valuable tool for understanding the complex interactions between hormones and their metabolic pathways.
Used in Hormonal Regulation:
Gestonorone is used as a hormonal regulator, helping to maintain the balance of sex hormones in the body. Its influence on body weight gain and the atrophy of reproductive organs highlights its potential in treating conditions where hormonal regulation is crucial.
Used in Endocrinology:
In the field of endocrinology, Gestonorone is used as a therapeutic agent for conditions related to hormonal imbalances. Its effects on body weight and reproductive organs make it a candidate for the treatment of various endocrine disorders.
Used in Reproductive Health:
Gestonorone is used in reproductive health as a progestational agent, playing a role in the regulation of the menstrual cycle and the maintenance of pregnancy. Its impact on reproductive organs and hormonal balance makes it a valuable compound in the management of fertility and related health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 2137-18-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,3 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2137-18:
(6*2)+(5*1)+(4*3)+(3*7)+(2*1)+(1*8)=60
60 % 10 = 0
So 2137-18-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H28O3/c1-12(21)20(23)10-8-18-17-5-3-13-11-14(22)4-6-15(13)16(17)7-9-19(18,20)2/h11,15-18,23H,3-10H2,1-2H3
2137-18-0Relevant articles and documents
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Zaffaroni et al.
, p. 6110,6114 (1958)
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A PROCESS FOR THE PRODUCTION OF OF 19-NORPREGN-4-EN-3,20-DIONE-17.ALPHA.-OL (GESTONORONE) AND INTERMEDIATES THEREFOR
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, (2015/07/07)
The present invention relates to a new stereoselective process for the synthesis of 17(α)-17-acetyl-17-hydroxy-estr-4-en-3-one of formula (I), as well as to the new intermediates of the process. The 17(α)-17-acetyl-17-hy droxy-estr-4-en-3 -one (gestonorone) is an important intermediate in the synthesis of the active ingredients having progestogen activity - such as gestonorone capronate and nomegestroi acetate. Formulas (I), (II) and (III).
Novel 17-esters of 17α-hydroxy gestogens, compositions containing such compounds, processes for their preparation and methods of treatment therewith
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, (2008/06/13)
This invention relates to novel 17α-esters of gestogens having an antitumour activity and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and method of treatment therewith.