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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Gestonorone

Cas:2137-18-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Gestonorone supplier in China

Cas:2137-18-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Kono Chem Co.,Ltd

Product Name:Gestonorone 2137-18-0 Appearance & Physical State: White or almost white crystalline powder Density: 1.17 Melting Point: 222-224ºC

CAS:2137-18-0 Gestonorone with best price

Cas:2137-18-0

Min.Order:1 Kilogram

Negotiable

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers

Gestonorone2137-18-0

Cas:2137-18-0

Min.Order:1 Kilogram

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Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Gestonorone

Cas:2137-18-0

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Gestonorone 2137-18-0 GMP Manufacturer

Cas:2137-18-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

17-Hydroxy-19-nor-4-pregnene-3,20-dione

Cas:2137-18-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Competitve Price in stockCAS 2137-18-0 with competitive price

Cas:2137-18-0

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Gestonorone/ LIDE PHARMA- Factory supply / Best price

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

19-Norpregn-4-ene-3,20-dione,17-hydroxy- 2137-18-0

Cas:2137-18-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

19-Norpregn-4-ene-3,20-dione,17-hydroxy-

Cas:2137-18-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

Gestonorone CAS NO.: 2137-18-0CAS NO.: 2137-18-0

Cas:2137-18-0

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

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Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi

Top quality Gestonorone CAS 2137-18-0 with factory price

Cas:2137-18-0

Min.Order:10 Gram

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Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

1.Free sample(10-20g or enough to detection) and Unconditional assume respons 2.100% Natural porduct, without any synthetize ingredient 3.Manufacturer direct supply, provide OEM, R&D service 4.ISO/HACCP/KOSHER/GMP/FDA 5.Leading plant extract

CAS No.2137-18-0 Gestonorone

Cas:2137-18-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

19-Norpregn-4-ene-3,20-dione,17-hydroxy-

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co. Ltd. is located in Wuhan, Hubei province. We are one of the most professional company in pharm/chmecial industry for more than 10 years. We export to many countries and area with very competitive price, high quality, good ser

Gestonorone high quality

Cas:2137-18-0

Min.Order:1 Gram

FOB Price: $10.0

Type:Manufacturers

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

GESTONORONE CAS 2137-18-0

Cas:2137-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Gestonorone

Cas:2137-18-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Gestonorone

Cas:2137-18-0

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Senova Technology Company Limited

We have most reliable quality, competitive prices and full documents for this APIs 1. GMP WORKSHOP 2. DMF Appearance:White crystal powder Application:CAS:2137-18-0

Gestonorone

Cas:2137-18-0

Min.Order:100 Gram

Negotiable

Type:Trading Company

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Gestonorone CAS NO.: 2137-18-0CAS NO.: 2137-18-0 CAS NO.2137-18-0

Cas:2137-18-0

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Manufacturers

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Sinoway Industrial Co., Ltd.

Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API

99% up by HPLC Gestonorone 2137-18-0

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Dingyan Chem Co., Ltd

manufacture Application:The refence standard products, for lab use, also we could produce bigger quantity on yr requirement.

gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Manufacturers

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Manufacturers

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Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Gestonorone

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Gestonorone 2137-18-0Appearance:white powder Storage:room temperarure Application:industry use

Gestonorone 2137-18-0

Cas:2137-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

C20H27ClO3

C20H27ClO3

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
With iron; acetic acid at 60℃; for 3h; Reagent/catalyst; Temperature;97.97%
20,20-ethanediyldioxy-3-methoxy-19-nor-pregna-2,5(10)-dien-17-ol
14339-99-2

20,20-ethanediyldioxy-3-methoxy-19-nor-pregna-2,5(10)-dien-17-ol

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
With hydrogenchloride
17α-hydroxy-3-methoxy-19-norpregna-1,3,5(10)-trien-20-one
1624-58-4

17α-hydroxy-3-methoxy-19-norpregna-1,3,5(10)-trien-20-one

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: benzene; toluene-4-sulfonic acid / Entfernen des entstehenden Wassers
2: diethyl ether; lithium; liquid ammonia / anschliessend Behandeln mit Aethanol
3: methanol.HCl
View Scheme
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid; trimethyl orthoformate / dichloromethane / 2 h / 20 °C
2: sodium; ammonia / ethanol; water; tetrahydrofuran; tert-butyl alcohol / -60 °C / Inert atmosphere
3: hydrogenchloride / water; tetrahydrofuran / 0.33 h / 60 °C
View Scheme
3-hydroxy-19-norpregna-1,3,5(10),16-tetraen-20-one
101766-63-6

3-hydroxy-19-norpregna-1,3,5(10),16-tetraen-20-one

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: methanol; aqueous hydrogen peroxide; aq. NaOH solution
2: ethanol; aqueous KOH-solution
3: HBr; acetic acid / Hydrierung an Palladium/CaCO3 in Aethanol
4: benzene; toluene-4-sulfonic acid / Entfernen des entstehenden Wassers
5: diethyl ether; lithium; liquid ammonia / anschliessend Behandeln mit Aethanol
6: methanol.HCl
View Scheme
16α,17α-epoxy-17-acetyl-Δ1,3,5(10)-estratriene
67519-64-6

16α,17α-epoxy-17-acetyl-Δ1,3,5(10)-estratriene

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: ethanol; aqueous KOH-solution
2: HBr; acetic acid / Hydrierung an Palladium/CaCO3 in Aethanol
3: benzene; toluene-4-sulfonic acid / Entfernen des entstehenden Wassers
4: diethyl ether; lithium; liquid ammonia / anschliessend Behandeln mit Aethanol
5: methanol.HCl
View Scheme
16α,17-epoxy-3-methoxy-19-nor-pregna-1,3,5(10)-trien-20-one
111979-17-0

16α,17-epoxy-3-methoxy-19-nor-pregna-1,3,5(10)-trien-20-one

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: HBr; acetic acid / Hydrierung an Palladium/CaCO3 in Aethanol
2: benzene; toluene-4-sulfonic acid / Entfernen des entstehenden Wassers
3: diethyl ether; lithium; liquid ammonia / anschliessend Behandeln mit Aethanol
4: methanol.HCl
View Scheme
20,20-(ethylenedioxy)-3-methoxy-17α-hydroxy-19-norpregna-1,3,5(10)-triene
14328-46-2

20,20-(ethylenedioxy)-3-methoxy-17α-hydroxy-19-norpregna-1,3,5(10)-triene

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: diethyl ether; lithium; liquid ammonia / anschliessend Behandeln mit Aethanol
2: methanol.HCl
View Scheme
Multi-step reaction with 2 steps
1: sodium; ammonia / ethanol; water; tetrahydrofuran; tert-butyl alcohol / -60 °C / Inert atmosphere
2: hydrogenchloride / water; tetrahydrofuran / 0.33 h / 60 °C
View Scheme
Estrone
53-16-7

Estrone

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: sodium hydroxide / acetone; water / 2 h / Reflux
2.1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C
3.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C
4.1: sodium methylate / methanol / Reflux
4.2: 2 h / Reflux
5.1: toluene-4-sulfonic acid; trimethyl orthoformate / dichloromethane / 2 h / 20 °C
6.1: sodium; ammonia / ethanol; water; tetrahydrofuran; tert-butyl alcohol / -60 °C / Inert atmosphere
7.1: hydrogenchloride / water; tetrahydrofuran / 0.33 h / 60 °C
View Scheme
estrone 3-methyl ether
1624-62-0

estrone 3-methyl ether

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C
2.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C
3.1: sodium methylate / methanol / Reflux
3.2: 2 h / Reflux
4.1: toluene-4-sulfonic acid; trimethyl orthoformate / dichloromethane / 2 h / 20 °C
5.1: sodium; ammonia / ethanol; water; tetrahydrofuran; tert-butyl alcohol / -60 °C / Inert atmosphere
6.1: hydrogenchloride / water; tetrahydrofuran / 0.33 h / 60 °C
View Scheme
C22H32O4

C22H32O4

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 60℃; for 0.333333h;18.6 g
mestranol
72-33-3

mestranol

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C
2.1: sodium methylate / methanol / Reflux
2.2: 2 h / Reflux
3.1: toluene-4-sulfonic acid; trimethyl orthoformate / dichloromethane / 2 h / 20 °C
4.1: sodium; ammonia / ethanol; water; tetrahydrofuran; tert-butyl alcohol / -60 °C / Inert atmosphere
5.1: hydrogenchloride / water; tetrahydrofuran / 0.33 h / 60 °C
View Scheme
3-methoxy-21-(phenylsulfinyl)-19-norpregna-1(2),3(4),5(10),17(20),20-pentaene

3-methoxy-21-(phenylsulfinyl)-19-norpregna-1(2),3(4),5(10),17(20),20-pentaene

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium methylate / methanol / Reflux
1.2: 2 h / Reflux
2.1: toluene-4-sulfonic acid; trimethyl orthoformate / dichloromethane / 2 h / 20 °C
3.1: sodium; ammonia / ethanol; water; tetrahydrofuran; tert-butyl alcohol / -60 °C / Inert atmosphere
4.1: hydrogenchloride / water; tetrahydrofuran / 0.33 h / 60 °C
View Scheme
3-methoxy-17α-[(trimethylsilyl)oxy]estr-2,5(10)-dien-17-carbonitrile

3-methoxy-17α-[(trimethylsilyl)oxy]estr-2,5(10)-dien-17-carbonitrile

methyllithium
917-54-4

methyllithium

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Stage #1: 3-methoxy-17α-[(trimethylsilyl)oxy]estr-2,5(10)-dien-17-carbonitrile; methyllithium With N,N,N,N,-tetramethylethylenediamine In tert-butyl methyl ether at -40 - -30℃; for 1h;
Stage #2: With hydrogenchloride In tert-butyl methyl ether at -30 - 25℃; for 16h;
25.67 g
3-methoxyestra-2,5(10)-dien-17-one
17976-32-8

3-methoxyestra-2,5(10)-dien-17-one

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 2,6-di-tert-butyl-4-methyl-phenol / ethanol / 0.17 h / Inert atmosphere
1.2: 17 h / 20 - 63 °C / Inert atmosphere
2.1: 2,6-di-tert-butyl-4-methyl-phenol; 1H-imidazole / tert-butyl methyl ether; tetrahydrofuran / Inert atmosphere
3.1: N,N,N,N,-tetramethylethylenediamine / tert-butyl methyl ether / 1 h / -40 - -30 °C
3.2: 16 h / -30 - 25 °C
View Scheme
C22H33ClO3Si

C22H33ClO3Si

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
2: iron; acetic acid / 3 h / 60 °C
View Scheme
estra-4-ene-3,17-dione
734-32-7

estra-4-ene-3,17-dione

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium hydroxide; Tetrahydrothiopyran-4-one; acetic acid / methanol; ethanol / 25 h / 38 °C / Green chemistry
2: dmap / dichloromethane / 2 h / 32 °C
3: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
4: iron; acetic acid / 3 h / 60 °C
View Scheme
Multi-step reaction with 4 steps
1: sodium hydroxide; Tetrahydrothiopyran-4-one; acetic acid / methanol; ethanol / 25 h / 38 °C / Green chemistry
2: triethylamine / tetrachloromethane / 2 h / -6 °C
3: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
4: iron; acetic acid / 3 h / 60 °C
View Scheme
Multi-step reaction with 4 steps
1: sodium hydroxide; Tetrahydrothiopyran-4-one; acetic acid / methanol; ethanol / 25 h / 38 °C / Green chemistry
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / benzene / 2 h / 0 - 2 °C
3: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
4: iron; acetic acid / 3 h / 60 °C
View Scheme
17β-cyano-17α-hydroxy-19-norandrost-4-en-3-one

17β-cyano-17α-hydroxy-19-norandrost-4-en-3-one

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dmap / dichloromethane / 2 h / 32 °C
2: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
3: iron; acetic acid / 3 h / 60 °C
View Scheme
Multi-step reaction with 3 steps
1: triethylamine / tetrachloromethane / 2 h / -6 °C
2: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
3: iron; acetic acid / 3 h / 60 °C
View Scheme
Multi-step reaction with 3 steps
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / benzene / 2 h / 0 - 2 °C
2: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
3: iron; acetic acid / 3 h / 60 °C
View Scheme
Multi-step reaction with 3 steps
1: dmap; 1H-imidazole / toluene; acetone / 2 h / -1 - 0 °C
2: lithium diisobutylamide; chloro-trimethyl-silane; n-butyllithium / dichloromethane; chloroform / 1 h / -50 °C / Inert atmosphere
3: iron; acetic acid / 3 h / 60 °C
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

acetic anhydride
108-24-7

acetic anhydride

17α-acetoxy-19-norpregna-4-ene-3,20-dione
31981-44-9

17α-acetoxy-19-norpregna-4-ene-3,20-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 20℃; for 24h;95%
With toluene-4-sulfonic acid und Behandeln des Reaktionsprodukts mit methanol.KOH;
With toluene-4-sulfonic acid und Behandeln des Reaktionsprodukts mit methanol.HCl;
Isopropenyl acetate
108-22-5

Isopropenyl acetate

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17α-acetoxy-19-norpregna-4-ene-3,20-dione
31981-44-9

17α-acetoxy-19-norpregna-4-ene-3,20-dione

Conditions
ConditionsYield
Stage #1: Isopropenyl acetate; 17-alpha-Hydroxy-19-norprogesterone With toluene-4-sulfonic acid In dichloromethane; chloroform at 58 - 60℃; for 2h;
Stage #2: With hydrogenchloride In dichloromethane; chloroform; water at 60℃; Solvent; Temperature;
82.36%
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

3-ethoxy-17α-hydroxy-19-norpregna-4-en-20-one

3-ethoxy-17α-hydroxy-19-norpregna-4-en-20-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol at 20 - 80℃; for 1h;82%
n-hexanoic anhydride
2051-49-2

n-hexanoic anhydride

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

gestonorone caproate
1253-28-7

gestonorone caproate

Conditions
ConditionsYield
With toluene-4-sulfonic acid und anscliessendes Erwaermen mit methanol.HCl;
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

11β,17,21-trihydroxy-19-nor-pregn-4-ene-3,20-dione
54947-44-3

11β,17,21-trihydroxy-19-nor-pregn-4-ene-3,20-dione

Conditions
ConditionsYield
mit Hilfe von Homogenaten aus Nebennieren;
Multi-step reaction with 3 steps
1: THF; methanol; iodine / anschliessendes Behandeln mit wss.NaOH und Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton
2: aqueous methanol.KHCO3
3: mit Hilfe von Homogenaten aus Nebennieren
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

21-acetoxy-17-hydroxy-19-nor-pregn-4-ene-3,20-dione
124263-28-1

21-acetoxy-17-hydroxy-19-nor-pregn-4-ene-3,20-dione

Conditions
ConditionsYield
With tetrahydrofuran; methanol; iodine anschliessendes Behandeln mit wss.NaOH und Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton;
formic acid
64-18-6

formic acid

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

acetic anhydride
108-24-7

acetic anhydride

17-formyloxy-19-nor-pregn-4-ene-3,20-dione
13635-19-3

17-formyloxy-19-nor-pregn-4-ene-3,20-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

11β-hydroxy-estr-4-ene-3,17-dione
15313-96-9

11β-hydroxy-estr-4-ene-3,17-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: mit Hilfe von Homogenaten aus Nebennieren
2: NaBiO3; aqueous acetic acid
View Scheme
Multi-step reaction with 4 steps
1: THF; methanol; iodine / anschliessendes Behandeln mit wss.NaOH und Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton
2: aqueous methanol.KHCO3
3: mit Hilfe von Homogenaten aus Nebennieren
4: NaBiO3; aqueous acetic acid
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17,21-dihydroxy-19-nor-pregn-4-ene-3,20-dione
115184-02-6

17,21-dihydroxy-19-nor-pregn-4-ene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: THF; methanol; iodine / anschliessendes Behandeln mit wss.NaOH und Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton
2: aqueous methanol.KHCO3
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17,21-dihydroxy-19-nor-pregn-4-ene-3,11,20-trione
111901-74-7

17,21-dihydroxy-19-nor-pregn-4-ene-3,11,20-trione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: mit Hilfe von Homogenaten aus Nebennieren
2: CrO3; acetic acid
View Scheme
Multi-step reaction with 4 steps
1: THF; methanol; iodine / anschliessendes Behandeln mit wss.NaOH und Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton
2: aqueous methanol.KHCO3
3: mit Hilfe von Homogenaten aus Nebennieren
4: CrO3; acetic acid
View Scheme
kieselguhr

kieselguhr

dipropoxymethane
505-84-0

dipropoxymethane

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17α-propoxymethoxy-19-nor-4-pregnene-3,20-dione

17α-propoxymethoxy-19-nor-4-pregnene-3,20-dione

Conditions
ConditionsYield
With phosphorus pentaoxide In dichloromethane
kieselguhr

kieselguhr

formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17α-ethoxymethoxy-19-nor-4-pregnene-3,20-dione

17α-ethoxymethoxy-19-nor-4-pregnene-3,20-dione

Conditions
ConditionsYield
With phosphorus pentaoxide In dichloromethane
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17α-methoxymethoxy-19-nor-4-pregnene-3,20-dione

17α-methoxymethoxy-19-nor-4-pregnene-3,20-dione

Conditions
ConditionsYield
In Dimethoxymethane
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

3-ethoxy-17α-acetoxy-19-norpregna-3,5-diene-20-one

3-ethoxy-17α-acetoxy-19-norpregna-3,5-diene-20-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / 24 h / 20 °C
2: toluene-4-sulfonic acid / tetrahydrofuran / 24 h / 20 °C
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

6-formyl-3-ethoxy-17α-acetoxy-19-norpregna-3,5-diene-20-one
147508-40-5

6-formyl-3-ethoxy-17α-acetoxy-19-norpregna-3,5-diene-20-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / 24 h / 20 °C
2: toluene-4-sulfonic acid / tetrahydrofuran / 24 h / 20 °C
3: trichlorophosphate / -10 °C
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

17α-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione
58652-19-0

17α-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: toluene-4-sulfonic acid / 24 h / 20 °C
2: toluene-4-sulfonic acid / tetrahydrofuran / 24 h / 20 °C
3: trichlorophosphate / -10 °C
4: sodium tetrahydroborate / methanol / 20 °C
View Scheme
17-alpha-Hydroxy-19-norprogesterone
2137-18-0

17-alpha-Hydroxy-19-norprogesterone

nomegestrol acetate
58652-20-3

nomegestrol acetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: toluene-4-sulfonic acid / 24 h / 20 °C
2: toluene-4-sulfonic acid / tetrahydrofuran / 24 h / 20 °C
3: trichlorophosphate / -10 °C
4: sodium tetrahydroborate / methanol / 20 °C
5: 5%-palladium/activated carbon / ethanol; tetrahydrofuran / 0.75 h / Reflux
View Scheme

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