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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Estrone Manufacturer/High quality/Best price/In stock

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Estrone 53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance white or almost white crystalline powder white crystalline powder Identif

High purity 1,3,5(10)-Estratrien-3-ol-17-one CAS:53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

Assay:99% Specification:USP31 Appearance:white crystalline powder Usage: A metabolite of 17-Estradiol Packaging: as your requirement Synonyms: (8R,13S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-

CAS:53-16-7 Estrone

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hebei yanxi chemical co.,LTD.

Reason for Choosing us: 1): Superior Quality and Competitive Price: Our company is a renowned pharmaceutical manufacturer with more than 15 years experiences in China and all powders are supplying from our factory directly. 2): Fast ,Sa

Steroid 99% Purity Estrone cas:53-16-7 CAS NO.53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White Crystalline Powder Storage:Refrigerator Package:1kg/foi

Manufacturer supply Estrone CAS 53-16-7 with high purity

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $800.0

Type:Trading Company

inquiry

Hangzhou Think Chemical Co. Ltd

Estrone CAS No.:53-16-7 Name: Estrone Synonyms: 1,3,5(10)-Estratrien-3-ol-17-one; 3beta-Hydroxyestra-1,3,5(10)-trien-17-one; 3-Hydroxy-1,3,5(10)-estratrien-17-one; beta-Estrone Molecular Structure

High purity Estrone CAS No.:53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Estrone

Cas:53-16-7

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Estrone 53-16-7 GMP Manufacturer

Cas:53-16-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

Estrone

Cas:53-16-7

Min.Order:5 Milligram

Negotiable

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Estrone

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Estrone

Cas:53-16-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Estrone CAS NO:13425-31-5 Grade:Medical scientific research and export Molecular formula:C18H22O2 Molecular weight:270.3661 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data sto

Estrone/ CAS:53-16-7/Estrone raw material/ high-quality

Cas:53-16-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

tianfu-chem_ 1,3,5(10)-Estratrien-3-ol-17-one 53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

1,3,5(10)-Estratrien-3-ol-17-one

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

High Quality Powder Estrone CAS 53-16-7 Chemical Name estrone Synonyms Femidyn; Estrin; Estra-1,3,5(10)-trien-17-one, 3-hydroxy-; 3-Hydroxy-1,3,5(10)-estratrien-17-one; Estrone; Expand CAS No.

High Quality Powder Estrone

Cas:53-16-7

Min.Order:5 Kilogram

FOB Price: $45.0 / 60.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 53-16-7 with best quality

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

hot sell Estrone

Cas:53-16-7

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

1,3,5(10)-Estratrien-3-ol-17-one:CAS:53-16-7

Cas:53-16-7

Min.Order:1 Metric Ton

FOB Price: $20.0 / 30.0

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystalline powder Storage:Room temperature Package:1kg/drum, 25kg/drum Application:API Transportation:Express/Air/Sea Port:Any port in china

Estrone

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Estrogenic Raw Powder Steroids Estradiol Hormone Powder Estriol Estrone 53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Estrone 53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

1,3,5(10)-Estratrien-3-ol-17-one with CAS:53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

FOB Price: $604.0 / 630.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical i

Estrone manufacturer/inventory/factory price

Cas:53-16-7

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We generally use secure shipping methods that do not require you to do any customs clearance. Free shipping to your address without worrying about any customs issues. We have a professional customs clearance team to 100% guarantee the safe delivery o

Supply Highest Quality Estradiol Hormone Powder Estriol Estrone 53-16-7

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Estrone

Cas:53-16-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Estrone IN STOCK 99% CAS 53-16-7 CAS NO.53-16-7

Cas:53-16-7

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

China Supplier Estrone with high purity 99%

Cas:53-16-7

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

estradiol
50-28-2

estradiol

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With Cp*Ir(6,6'-dionato-2,2'-bipyridine)(H2O) In tert-butyl alcohol at 130℃; for 20h;100%
With Cp*Ir(6,6'-dionato-2,2'-bipyridine)(H2O) In tert-butyl alcohol for 20h; Reflux;100%
With polystyrene-supported(cathecholato) oxoRe cat. act by iPrOH; dimethyl sulfoxide In toluene for 4h; Heating; Dean-Stark apparatus;98%
R-estradiol
493001-46-0

R-estradiol

tert-butyl alcohol
75-65-0

tert-butyl alcohol

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
100%
estrone acetate
901-93-9

estrone acetate

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With methanol; zinc98%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 27℃; for 72h;94%
With lipase from Candida cylindracea; octanol In various solvent(s) at 37℃; for 144h;90%
With sodium hydroxide In methanol; water for 0.25h;
17-oxo-1,3,5(10)-estratrien-3-yl 2-(trimethylsilyl)ethyl butanedioate
92803-51-5

17-oxo-1,3,5(10)-estratrien-3-yl 2-(trimethylsilyl)ethyl butanedioate

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 27℃; for 24h;97%
10β-hydroxy-19-norandrost-4-ene-3,17-dione
5189-96-8

10β-hydroxy-19-norandrost-4-ene-3,17-dione

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In diethyl ether Ambient temperature;96%
With toluene-4-sulfonic acid In diethyl ether Ambient temperature; Yield given;
With acetic acid In chloroform-d1
C23H34O3Si
1422954-71-9

C23H34O3Si

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 20℃; for 2h;95%
estrone 3-methyl ether
1624-62-0

estrone 3-methyl ether

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With aluminium trichloride; sodium iodide In dichloromethane; acetonitrile for 5.5h; Heating;93%
Stage #1: estrone 3-methyl ether With aluminum (III) chloride; sodium iodide In dichloromethane at 0 - 20℃; Inert atmosphere;
Stage #2: With hydrogenchloride; water In dichloromethane Inert atmosphere;
92%
With boron tribromide at -30 - 0℃; for 2.5h;88%
19-acetoxyandrosta-1,4-diene-3,17-dione
95282-98-7

19-acetoxyandrosta-1,4-diene-3,17-dione

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; for 0.05h;90%
With sodium hydroxide In methanol at 20℃; for 2h;76%
With potassium hydroxide In methanol at 20℃; for 2h;50.1%
(polystyrene resin Novabiochem)-C6H4(C6H5)2CNHSO2O-3-estrone

(polystyrene resin Novabiochem)-C6H4(C6H5)2CNHSO2O-3-estrone

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With diethylamine In ethanol; dichloromethane at 55 - 60℃; for 8h; Hydrolysis;90%
3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>estra-1,3,5(10)-trien-17-one
90850-47-8

3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>estra-1,3,5(10)-trien-17-one

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With sodium methylate In N,N-dimethyl-formamide at 20℃; for 2h; Product distribution; regeneration reactions of the parent compound from different perfluoroaryl derivatives to the alcohols; other educts and products, different times, temperatures and mol ratios of the educts;87%
19-tert-butyldimethylsilyloxy-androsta-1,4-diene-3,17-dione
194094-44-5

19-tert-butyldimethylsilyloxy-androsta-1,4-diene-3,17-dione

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 2h;85.9%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 1h;
4β,5-epoxy-5β-androstane-3,17,19-trione
84882-46-2

4β,5-epoxy-5β-androstane-3,17,19-trione

A

Estrone
53-16-7

Estrone

B

4β,5-dihydroxy-5α-androstane-3,17,19-trione 4,19-hemiacetal
84882-49-5

4β,5-dihydroxy-5α-androstane-3,17,19-trione 4,19-hemiacetal

Conditions
ConditionsYield
With perchloric acid In tetrahydrofuran; water for 72h;A 3%
B 82%
(8R,9S,13S,14S)-13-Methyl-3-[1-(2-trimethylsilanyl-ethoxy)-ethoxy]-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one

(8R,9S,13S,14S)-13-Methyl-3-[1-(2-trimethylsilanyl-ethoxy)-ethoxy]-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 45℃; for 20h;82%
estradiol
50-28-2

estradiol

ethylene glycol
107-21-1

ethylene glycol

A

Estrone
53-16-7

Estrone

B

(8R,9S,13S,14S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2′-[1,3]dioxolan]-3-ol
900-83-4

(8R,9S,13S,14S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2′-[1,3]dioxolan]-3-ol

Conditions
ConditionsYield
With dimethyl sulfoxide; [ReOCl3(PPh3)2] In toluene for 5h; Heating;A 18%
B 82%
3-benzyloxyestra-1,3,5(10)-trien-17-one
858-98-0

3-benzyloxyestra-1,3,5(10)-trien-17-one

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In tetrahydrofuran; methanol at 40℃; for 12h;81%
With palladium on activated charcoal; hydrogen In methanol at 40℃; for 12h;81%
2α-acetoxy-19-oxoandrost-4-ene-3,17-dione
124522-65-2

2α-acetoxy-19-oxoandrost-4-ene-3,17-dione

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With potassium hydrogencarbonate In methanol; water for 2h; Ambient temperature; further reagents;80%
3,17-dioxo-4β,5-epoxy-5β-androstan-19-oic acid
76251-10-0

3,17-dioxo-4β,5-epoxy-5β-androstan-19-oic acid

A

Estrone
53-16-7

Estrone

B

(8R,9S,13S,14S)-3-Hydroxy-13-methyl-2,3,6,7,8,9,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-4,17-dione
76251-11-1, 76251-12-2

(8R,9S,13S,14S)-3-Hydroxy-13-methyl-2,3,6,7,8,9,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-4,17-dione

Conditions
ConditionsYield
In decalin for 2.5h; Heating;A 9%
B 79%
3β-Hydroxy-19-norandrosta-1(10),5-dien-17-one
843-81-2

3β-Hydroxy-19-norandrosta-1(10),5-dien-17-one

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With 1-Methyl-4-piperidone; aluminum isopropoxide In toluene for 4h; Heating;77%
Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With iodine; triethylphosphine In toluene at 120℃; for 10h; Concentration; Solvent; Reagent/catalyst; Temperature;72%
With mineral oil at 530℃; in ein mit Glasperlen beschicktes Rohr;
at 325℃; unter vermindertem Druck;
at 325℃;
2,4-dibromo-3-hydroxy-13β-estra-1,3,5(10)-trien-17-one
60788-62-7

2,4-dibromo-3-hydroxy-13β-estra-1,3,5(10)-trien-17-one

A

Estrone
53-16-7

Estrone

B

4-bromo-3-hydroxyestra-1,3,5(10)-trien-17-one
1630-82-6

4-bromo-3-hydroxyestra-1,3,5(10)-trien-17-one

Conditions
ConditionsYield
With formic acid; palladium on activated charcoal In N,N-dimethyl-formamide for 1.75h; Heating;A 20%
B 70%
With formic acid; palladium on activated charcoal In N,N-dimethyl-formamide for 1.75h; Heating; variation in time and temperature;A 20%
B 70%
With hydrogen; palladium on activated charcoal In ethanol Ambient temperature; Yield given;
estrone-3′-hemisuccinate
58534-72-8

estrone-3′-hemisuccinate

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 27℃; for 32h;66%
(3aS,3bR,9bS,11aS)‐11a‐methyl‐7‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)‐1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH‐cyclopenta[a]phenanthren‐1‐one

(3aS,3bR,9bS,11aS)‐11a‐methyl‐7‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)‐1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH‐cyclopenta[a]phenanthren‐1‐one

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With [Rh2(bpy)2(μ-OAc)2(OAc)2]; oxygen; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide under 760.051 Torr; for 24h; Irradiation;63%
17-oxo-estra-1,3,5(10)-trien-3-yl Se-phenyl selenocarbonate
76920-48-4

17-oxo-estra-1,3,5(10)-trien-3-yl Se-phenyl selenocarbonate

A

Estrone
53-16-7

Estrone

B

estrone formate

estrone formate

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In xylene at 144℃;A 62%
B 18%
estradiol
145164-84-7

estradiol

Estrone
53-16-7

Estrone

Conditions
ConditionsYield
With 2,6-di-tert-butyl-4-methyl-phenol; aluminum isopropoxide; benzaldehyde In 2-methyltetrahydrofuran at 20℃; for 4h; Oppenauer Oxidation; Inert atmosphere;58%
C20H26O3

C20H26O3

A

Estrone
53-16-7

Estrone

B

3-Hydroxy-9β-estra-1,3,5(10)-trien-17-one
1225-03-2

3-Hydroxy-9β-estra-1,3,5(10)-trien-17-one

Conditions
ConditionsYield
With hydrogenchloride In methanol; water at 20 - 25℃; for 0.5h; Inert atmosphere;A 56%
B 32%
3β-Hydroxy-19-norandrosta-1(10),5-dien-17-one
843-81-2

3β-Hydroxy-19-norandrosta-1(10),5-dien-17-one

A

Estrone
53-16-7

Estrone

B

17-Oxo-19-norandrost-1(10),5-dien-3β-yl trifluoroacetate
116202-05-2

17-Oxo-19-norandrost-1(10),5-dien-3β-yl trifluoroacetate

Conditions
ConditionsYield
With triethylamine In dichloromethane; dimethyl sulfoxide at -78℃;A 53%
B 20%
3β-Hydroxy-19-norandrosta-1(10),5-dien-17-one
843-81-2

3β-Hydroxy-19-norandrosta-1(10),5-dien-17-one

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

A

Estrone
53-16-7

Estrone

B

17-Oxo-19-norandrost-1(10),5-dien-3β-yl trifluoroacetate
116202-05-2

17-Oxo-19-norandrost-1(10),5-dien-3β-yl trifluoroacetate

Conditions
ConditionsYield
With triethylamine In dichloromethane; dimethyl sulfoxide at -78℃;A 53%
B 20%
C18H24O3

C18H24O3

A

Estrone
53-16-7

Estrone

B

10β-hydroxy-19-norandrost-4-ene-3,17-dione
5189-96-8

10β-hydroxy-19-norandrost-4-ene-3,17-dione

Conditions
ConditionsYield
With acetic acid for 1.33333h; Heating;A 18%
B 50%
4β,5-epoxy-5β-androstane-3,17,19-trione
84882-46-2

4β,5-epoxy-5β-androstane-3,17,19-trione

A

Estrone
53-16-7

Estrone

B

A-nor-5β-androstane-3,17,19-trione

A-nor-5β-androstane-3,17,19-trione

C

4β,5-dihydroxy-5α-androstane-3,17,19-trione 4,19-hemiacetal
84882-49-5

4β,5-dihydroxy-5α-androstane-3,17,19-trione 4,19-hemiacetal

D

4-hydroxyandrost-4-ene-3,17,19-trione

4-hydroxyandrost-4-ene-3,17,19-trione

Conditions
ConditionsYield
With perchloric acid In tetrahydrofuran for 24h;A 8%
B 7%
C 17%
D 49%
With perchloric acid In tetrahydrofuran for 24h; Product distribution; reaction in the presence of H2SO4; acid- and base-catalysed reactions of 4β,5β- and 4α,5α-epoxyandrostane-3,17,19-triones;A 8%
B 7%
C 17%
D 49%
Estrone
53-16-7

Estrone

3-hydroxy-estra-1,3,5(10)-trien-17-one oxime
5982-51-4

3-hydroxy-estra-1,3,5(10)-trien-17-one oxime

Conditions
ConditionsYield
With pyridine; hydroxylamine hydrochloride In ethanol; water for 6h; Reflux; Inert atmosphere;100%
With pyridine; hydroxylamine hydrochloride In ethanol for 6h; Reflux;100%
With hydroxylamine hydrochloride In pyridine; ethanol99%
Estrone
53-16-7

Estrone

17β-hydrazoestra-1,3,5(10)-trien-3-ol
7628-02-6

17β-hydrazoestra-1,3,5(10)-trien-3-ol

Conditions
ConditionsYield
With triethylamine; hydrazine In ethanol; water100%
With triethylamine; hydrazine In ethanol for 3h; Reflux;96%
With hydrazine hydrate In ethanol at 45℃; for 2h;95%
With hydrazine
With hydrazine In butan-1-ol; diethylene glycol for 1h; Reflux;
Estrone
53-16-7

Estrone

pivaloyl chloride
3282-30-2

pivaloyl chloride

(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl pivalate
4003-22-9

(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl pivalate

Conditions
ConditionsYield
With triethylamine In chloroform100%
With dmap; triethylamine In dichloromethane at 0℃; for 0.3h; Inert atmosphere;96%
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere; Sealed tube;87%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

Estrone
53-16-7

Estrone

3-tetrahydropyranyloxy-1,3,5(10)-estratrien-17-one
7103-48-2

3-tetrahydropyranyloxy-1,3,5(10)-estratrien-17-one

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane at 23℃; for 18h;100%
With pyridinium p-toluenesulfonate In dichloromethane at 21℃; for 20h;100%
With pyridinium p-toluenesulfonate In dichloromethane at 23℃; for 18h;100%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

Estrone
53-16-7

Estrone

estrone triflate
92817-04-4

estrone triflate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; Inert atmosphere;100%
With pyridine In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;100%
With triethylamine In dichloromethane at 0℃; for 1h;99%
Estrone
53-16-7

Estrone

ethylene glycol
107-21-1

ethylene glycol

(8R,9S,13S,14S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2′-[1,3]dioxolan]-3-ol
900-83-4

(8R,9S,13S,14S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2′-[1,3]dioxolan]-3-ol

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
With trimethyl orthoformate In toluene; acetonitrile at 20℃;99%
With toluene-4-sulfonic acid In benzene for 13h; Heating;94%
Estrone
53-16-7

Estrone

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl methanesulfonate
3381-23-5

(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl methanesulfonate

Conditions
ConditionsYield
With pyridine Ambient temperature;100%
In dichloromethane Heating;92%
With triethylamine In dichloromethane for 3h;91%
With triethylamine In dichloromethane 0 deg C to r.t., 24 h;88%
With pyridine at 0 - 25℃;
Estrone
53-16-7

Estrone

D-camphor-10-sulfonyl chloride
21286-54-4, 39262-22-1

D-camphor-10-sulfonyl chloride

estrone-3-((+)-10-camphor)sulfonate

estrone-3-((+)-10-camphor)sulfonate

Conditions
ConditionsYield
With pyridine Ambient temperature;100%
Estrone
53-16-7

Estrone

aminooxyacetic acid
645-88-5

aminooxyacetic acid

2-({(E)-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-ylidene]amino}oxy)acetic acid
16218-61-4

2-({(E)-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-ylidene]amino}oxy)acetic acid

Conditions
ConditionsYield
With pyridine at 20℃; for 17h;100%
triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

Estrone
53-16-7

Estrone

(8R,9S,13S,14S)-13-Methyl-3-triisopropylsilanyloxy-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one

(8R,9S,13S,14S)-13-Methyl-3-triisopropylsilanyloxy-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide Inert atmosphere;100%
Estrone
53-16-7

Estrone

ethylene dibromide
106-93-4

ethylene dibromide

3-(2’-bromoethoxy)estra-1,3,5(10)-trien-17-one
191155-58-5

3-(2’-bromoethoxy)estra-1,3,5(10)-trien-17-one

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; water Reflux;100%
With sodium hydroxide In tetrahydrofuran; water Reflux;84%
Estrone
53-16-7

Estrone

benzoyl chloride
98-88-4

benzoyl chloride

estrone 3-benzoate
2393-53-5

estrone 3-benzoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20 - 30℃;100%
With pyridine at 25℃;95%
With pyridine for 2h; Inert atmosphere;94%
Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

Estrone
53-16-7

Estrone

methyl 4-((((8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)oxy)methyl)benzoate

methyl 4-((((8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)oxy)methyl)benzoate

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; potassium carbonate In acetone for 48h; Schlenk technique; Inert atmosphere; Reflux;100%
With tetra-(n-butyl)ammonium iodide; potassium carbonate In acetone for 48h; Schlenk technique; Inert atmosphere; Reflux;100%
Br(CH2)2OCH3

Br(CH2)2OCH3

Estrone
53-16-7

Estrone

3-(2'-Methoxyethoxy)-1,3,5(10)-estratrien-17-one
243638-26-8

3-(2'-Methoxyethoxy)-1,3,5(10)-estratrien-17-one

Conditions
ConditionsYield
With caesium carbonate In acetonitrile99.4%
trifluoromethane sulfonyl chloride
421-83-0

trifluoromethane sulfonyl chloride

Estrone
53-16-7

Estrone

estrone triflate
92817-04-4

estrone triflate

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃; for 0.25h; Inert atmosphere;99%
With triethylamine91%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 6h; Inert atmosphere;82%
Estrone
53-16-7

Estrone

16,16-di-deuterium-estra-1,3,5(10)-triene-17-one
56588-58-0

16,16-di-deuterium-estra-1,3,5(10)-triene-17-one

Conditions
ConditionsYield
With [D]-sodium hydroxide In deuteromethanol; water-d2 for 24h; Reflux; Inert atmosphere;99%
With deuteriated sodium hydroxide In deuteromethanol; water-d2 at 60℃; for 24h;
With deuteromethanol; sodium methylate
Estrone
53-16-7

Estrone

ethane-1,2-dithiol
540-63-6

ethane-1,2-dithiol

C20H26OS2
14485-61-1

C20H26OS2

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene Heating;99%
With toluene-4-sulfonic acid In toluene Reflux;
Estrone
53-16-7

Estrone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3-(O-tert-butyl(dimethyl)silyl)estrone
57711-40-7

3-(O-tert-butyl(dimethyl)silyl)estrone

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1h;99%
With 1H-imidazole99%
With 1H-imidazole In DMF (N,N-dimethyl-formamide) at 20℃;98%
Estrone
53-16-7

Estrone

methyl iodide
74-88-4

methyl iodide

estrone 3-methyl ether
1624-62-0

estrone 3-methyl ether

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; sodium hydroxide In dichloromethane at 70℃; for 3h;99%
With potassium carbonate In N,N-dimethyl-formamide Heating;98%
With potassium carbonate In N,N-dimethyl-formamide 1) reflux, 2 h, 2) r.t., 5 d;97%
Estrone
53-16-7

Estrone

benzyl bromide
100-39-0

benzyl bromide

3-benzyloxyestra-1,3,5(10)-trien-17-one
858-98-0

3-benzyloxyestra-1,3,5(10)-trien-17-one

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane for 24h; Heating;99%
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane for 24h; Heating;99%
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane; water for 24h; Heating / reflux;99%
Estrone
53-16-7

Estrone

(aminooxy)acetic acid hemihydrochloride
2921-14-4, 7776-18-3, 20295-82-3

(aminooxy)acetic acid hemihydrochloride

2-({(E)-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-ylidene]amino}oxy)acetic acid
16218-61-4

2-({(E)-[(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-ylidene]amino}oxy)acetic acid

Conditions
ConditionsYield
With pyridine at 23℃; for 16h;99%
Isopropenyl acetate
108-22-5

Isopropenyl acetate

Estrone
53-16-7

Estrone

estrone acetate
901-93-9

estrone acetate

Conditions
ConditionsYield
With iron(III) trifluoromethanesulfonate at 20℃; for 5h; Schlenk technique;99%
With iodine at 85 - 90℃; for 0.0833333h;96%
With iodine at 90℃;
1H-imidazole
288-32-4

1H-imidazole

Estrone
53-16-7

Estrone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3-tert-butyldimethylsilyloxy-estra-1,3,5(10)-triene-17-one

3-tert-butyldimethylsilyloxy-estra-1,3,5(10)-triene-17-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide99%
In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide94%
1H-imidazole
288-32-4

1H-imidazole

Estrone
53-16-7

Estrone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

A

3-tert-butyldimethylsilyloxy-estra-1,3,5(10)-triene-17-one

3-tert-butyldimethylsilyloxy-estra-1,3,5(10)-triene-17-one

B

[17(20)E]-Carbethoxymethylideneestra-1,3,5(10)-trieno-[3,2,e]-1',2',3'-oxathiazine-2,2'-dioxide

[17(20)E]-Carbethoxymethylideneestra-1,3,5(10)-trieno-[3,2,e]-1',2',3'-oxathiazine-2,2'-dioxide

Conditions
ConditionsYield
In N,N-dimethyl-formamideA 99%
B n/a
Estrone
53-16-7

Estrone

C18H19(2)H3O2
1021878-04-5

C18H19(2)H3O2

Conditions
ConditionsYield
With hydrogen; water-d2; palladium on activated charcoal at 20℃; for 72h;99%
Estrone
53-16-7

Estrone

di-tert-butylchlorosilane
56310-18-0

di-tert-butylchlorosilane

C26H40O3Si
1315577-32-2

C26H40O3Si

Conditions
ConditionsYield
Stage #1: Estrone; di-tert-butylchlorosilane With 1H-imidazole In tetrahydrofuran at 20℃; Inert atmosphere;
Stage #2: With N-Bromosuccinimide In dichloromethane
Stage #3: With water; sodium hydroxide In dichloromethane; N,N-dimethyl-formamide at 20℃;
99%
Estrone
53-16-7

Estrone

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

estrone 3-methyl ether
1624-62-0

estrone 3-methyl ether

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 130℃; for 16h;99%
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