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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

tert-Butyldimethylsilyl chloride Manufacturer/High quality/Best price/In stock

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Shandong Xinhua Pharmaceutical Co.,Ltd

best price ,best quality capacity 500mt/y Application:Pharamceutical intermediate

Tert-butyl dimethyl chloro silane

Cas:18162-48-6

Min.Order:100 Kilogram

Negotiable

Type:Manufacturers

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LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:0

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Type:Trading Company

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/2014.html Product Name tert-Butyldimethylsilyl chloride CAS No. 18162-48-6

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality tbms supplier in China

Cas:18162-48-6

Min.Order:1 Kilogram

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Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High purity tert-Butyldimethylsilyl chloride CAS 18162-48-6 with fast delivery Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates,

High purity tert-Butyldimethylsilyl chloride CAS 18162-48-6 with fast delivery

Cas:18162-48-6

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

Tert-Butyldimethylsilyl Chloride[CAS:18162-48-6],TBSCl HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing

Good supplierTert-Butyldimethylsilyl Chloride for Fulvestrant

Cas:18162-48-6

Min.Order:10 Gram

Negotiable

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply tert-butylchlorodimethylsilane

Cas:18162-48-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Silane,chloro(1,1-dimethylethyl)dimethyl- 18162-48-6 ISO Manufacturer

Cas:18162-48-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $5.0 / 10.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

tert-Butylchlorodimethylsilane

Cas:18162-48-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU-CHEM 18162-48-6 tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 18162-48-6 with best quality

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: tert-Butyldimethylsilyl chloride Molecular Formula:C6H15ClSi Molecular Weight:150.73 CAS No.:18162-48-6 Appearance:Similar White To Slight Greycrystal Appearance:Similar White To Slight Greycrystal Storage:Store in cool and dry place, away

tert-Butyldimethylsilyl chloride CAS:18162-48-6

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

tert-butyldimethylsilyl chloride manufacturer with low price

Cas:18162-48-6

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White crystalline granules or powder. Storage:Store in seale

tert-Butyldimethylsilyl chloride/TBSCl CAS No.:18162-48-6

Cas:18162-48-6

Min.Order:100 Gram

Negotiable

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Silane,chloro(1,1-dimethylethyl)dimethyl- 18162-48-6

Cas:18162-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

tert-Butyldimethylsilyl chloride Chemical Properties Melting point 86-89 °C (lit.) Boiling point 125 °C (lit.) density 0.87 g/mL at 20 °C(lit.) refractive index n20/D 1.46 Fp 73 °F storage temp. Store below +30

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Chemical Intermediate tert-Butyldimethylsilyl chloride CAS:18162-48-6

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $96.0 / 98.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

tert-Butyldimethylsilyl chloride CAS:18162-48-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

tert-Butyldimethylsilyl chloride CAS:18162-48-6

Cas:18162-48-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail bes

99% Tert-Butyldimethylsilyl chloride CAS:18162-48-6

Cas:18162-48-6

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Silane,chloro(1,1-dimethylethyl)dimethyl-

Cas:18162-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Lonwin Chemical Group Limited

tert-Butyldimethylsilyl chloride CAS: 18162-48-6 Specification Item Specification Appearance White Powder Assay 98%min Density 0.87 g/mL at 20 °C(lit.) Melting Point 86-89 °C (lit

Factory supply tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Kilogram

Negotiable

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Silane,chloro(1,1-dimethylethyl)dimethyl-

Cas:18162-48-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Tert-butylchlorodiMethylsilane

Cas:18162-48-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

tert-Butyldimethylchlorosilane in China /favorable price /best quality 18162-48-6

Cas:18162-48-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Couri

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

tert-Butyldimethylsilyl chloride

Cas:18162-48-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 100000.0

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Tert-butylchlorodiMethylsilane

Cas:18162-48-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Synthetic route

tert-butyldimethylsilane
29681-57-0

tert-butyldimethylsilane

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
palladium diacetate99.8%
tert-butyl(dimethyl)(phenylseleno)silane
72726-46-6

tert-butyl(dimethyl)(phenylseleno)silane

A

diphenyl diselenide
1666-13-3

diphenyl diselenide

B

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With chlorine In tetrachloromethaneA 96%
B 93%
phosgene
75-44-5

phosgene

chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

tert-butyldimethylsilanol
18173-64-3

tert-butyldimethylsilanol

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
In N,N-dimethyl-formamide96%
phosgene
75-44-5

phosgene

chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

tert-butyldimethylsilanol
18173-64-3

tert-butyldimethylsilanol

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

N-methyl-N-phenylformamide
93-61-8

N-methyl-N-phenylformamide

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
92%
tert-butyldimethylsilane
29681-57-0

tert-butyldimethylsilane

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With hexachloroethane; palladium dichloride In tetrahydrofuran at 20℃; for 2h;89%
With tetrabutylammonium perchlorate; copper(l) chloride In 1,2-dimethoxyethane electrochemical reaction;83%
With copper(l) iodide; copper dichloride In tetrahydrofuran; diethyl ether at 20℃; for 60h;73%
tri-t-butylsilane
18159-55-2

tri-t-butylsilane

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With hydrogenchloride; palladium on activated charcoal In hexane at 25℃; for 2h;87%
tertiary butyl chloride
507-20-0

tertiary butyl chloride

dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With magnesium In tetrahydrofuran; hexane78%
With copper(l) cyanide; magnesium In tetrahydrofuran for 2h; Heating;74%
di(methyl)tert-butyl(methoxy)silane
66548-21-8

di(methyl)tert-butyl(methoxy)silane

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With hydrogenchloride In water at 20℃; for 10h;78%
With hydrogenchloride In hexane at 0℃; for 2h;71%
With hydrogenchloride In water at 20℃; for 5 - 10h; Product distribution / selectivity;60%
tert.-butyl lithium
594-19-4

tert.-butyl lithium

dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
In pentane for 2h; Heating;61%
dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With t-C4H9Li In not given58%
With tert.-butyl lithium In not given58%
bis(trifluoromethyl)germanium chloride
66348-17-2

bis(trifluoromethyl)germanium chloride

1,3-di-tert-butyl-1,1,3,3-tetramethyldisilatellurane
80594-86-1

1,3-di-tert-butyl-1,1,3,3-tetramethyldisilatellurane

A

bistris(trifluoromethyl)germyl telluride
112438-43-4

bistris(trifluoromethyl)germyl telluride

B

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
Ar atmosphere, heating (80°C, 2 d); protection against light; fractional sublimation; elem. anal.;A 52%
B n/a
tert-butyldimethylsilanol
18173-64-3

tert-butyldimethylsilanol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With thionyl chloride In chloroform for 0.5h;39%
With hydrogenchloride In hexane at 0℃; for 2h;98 % Chromat.
tert-butyldimethylfluorosilane
2357-76-8

tert-butyldimethylfluorosilane

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
With chloro-trimethyl-silane; aluminium trichloride
1-(tert-butyldimethylsilyloxy)-1-isopropoxycyclopropane
96760-01-9

1-(tert-butyldimethylsilyloxy)-1-isopropoxycyclopropane

A

isopropyl chloride
75-29-6

isopropyl chloride

B

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

C

isopropyl 3-(trichlorotitanio)propionate

isopropyl 3-(trichlorotitanio)propionate

D

C9H19Cl3O2SiTi

C9H19Cl3O2SiTi

Conditions
ConditionsYield
With titanium tetrachloride In chloroform-d1 Product distribution; Mechanism;
Aminodichlorphosphan
85909-11-1

Aminodichlorphosphan

A

C6H15ClNPSi

C6H15ClNPSi

B

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
at 319.84℃; Thermolysis;
2-(trimethylsilyl)propene
18163-07-0

2-(trimethylsilyl)propene

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NH4F*HF, H2SO4
2: ClSiMe3, AlCl3
View Scheme
1H-imidazole
288-32-4

1H-imidazole

7'-chloro-4'-methylfluorescein
389625-48-3

7'-chloro-4'-methylfluorescein

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
In N,N-dimethyl-formamide
tert-butylmagnesium chloride
677-22-5

tert-butylmagnesium chloride

dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1H-imidazole
288-32-4

1H-imidazole

(2R)-4-(3-pyridyl)-1,2-butanediol
192376-55-9

(2R)-4-(3-pyridyl)-1,2-butanediol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

A

(2R)-2-(tert-butyldimethylsilyloxy)-4-(pyridin-3-yl)-1-(4-toluenesulfonyloxy)butane
192376-56-0

(2R)-2-(tert-butyldimethylsilyloxy)-4-(pyridin-3-yl)-1-(4-toluenesulfonyloxy)butane

B

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
In pyridine; dichloromethane
tert-butyldimethylsilane
29681-57-0

tert-butyldimethylsilane

copper(I) iodide
7681-65-4

copper(I) iodide

copper(II) chloride
7447-39-4

copper(II) chloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
In tetrahydrofuran
1,2-dimethoxybenzene
91-16-7

1,2-dimethoxybenzene

tert-butyldimethylsilane
29681-57-0

tert-butyldimethylsilane

dimethylsilicon dichloride
75-78-5

dimethylsilicon dichloride

A

dimethylmonochlorosilane
1066-35-9

dimethylmonochlorosilane

B

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
AlCl3A n/a
B 91% and 92%
1H-imidazole
288-32-4

1H-imidazole

potassium hydrogensulfate
7646-93-7

potassium hydrogensulfate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

Conditions
ConditionsYield
In N-methyl-acetamide
2,2'-Anhydrouridine
3736-77-4

2,2'-Anhydrouridine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(2R,3R,3aS,9aR)-3-((tert-butyldimethylsilyl)oxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)-3,3a-dihydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6(9aH)-one
55264-11-4

(2R,3R,3aS,9aR)-3-((tert-butyldimethylsilyl)oxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)-3,3a-dihydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6(9aH)-one

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 2h; Inert atmosphere;100%
With 1H-imidazole In N,N-dimethyl-formamide for 3h; Ambient temperature;92%
With pyridine; 1H-imidazole Ambient temperature;61%
With 1H-imidazole
With 1H-imidazole In N,N-dimethyl-formamide for 1h;
1-Octyn-3-ol
818-72-4

1-Octyn-3-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3-(tert-butyldimethylsilyloxy)oct-1-yne
60134-93-2

3-(tert-butyldimethylsilyloxy)oct-1-yne

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 8h; Ambient temperature;100%
With 1H-imidazole silylation;99%
With 1H-imidazole; dmap In dichloromethane at 0 - 20℃; for 20h;99%
glycolic Acid
79-14-1

glycolic Acid

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(tert-butyldimethylsiloxy) acetic acid tert-butyldimethylsilyl ester
67226-76-0

(tert-butyldimethylsiloxy) acetic acid tert-butyldimethylsilyl ester

Conditions
ConditionsYield
With pyridine for 2h; Ambient temperature;100%
With 1H-imidazole In N,N-dimethyl-formamide for 10h; Ambient temperature;97%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 16h;95%
pent-1-yn-5-ol
5390-04-5

pent-1-yn-5-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-(tert-butyldimethylsilyloxy)-4-pentyne
61362-77-4

1-(tert-butyldimethylsilyloxy)-4-pentyne

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 25℃;100%
With 1H-imidazole In N,N-dimethyl-formamide at 25℃; for 4h; Inert atmosphere;100%
With 1H-imidazole In dichloromethane at 0 - 20℃; for 0.5h; Inert atmosphere;100%
cyclopent-3-enol
14320-38-8

cyclopent-3-enol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

4-tert-butyldimethylsilyloxycyclopentene
68845-72-7

4-tert-butyldimethylsilyloxycyclopentene

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃;100%
With 1H-imidazole In dichloromethane at 0 - 20℃; for 16.5h;100%
With 1H-imidazole In tetrahydrofuran at 0℃;95%
tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

benzyl alcohol
100-51-6

benzyl alcohol

(benzyloxy)(tert-butyl)dimethylsilane
53172-91-1

(benzyloxy)(tert-butyl)dimethylsilane

Conditions
ConditionsYield
With P(MeN(CH3)CH2CH2)3N; triethylamine In acetonitrile at 24℃; for 2.5h;100%
With ferric hydrogen sulphate; triethylamine In acetonitrile at 20℃; for 60h; Inert atmosphere; chemoselective reaction;100%
With 1H-imidazole; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 20℃; for 0.5h;99%
tetrahydrofuran
109-99-9

tetrahydrofuran

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-{[dimethyl(1,1-dimethylethyl)silyl]oxy}-4-iodobutane
92511-12-1

1-{[dimethyl(1,1-dimethylethyl)silyl]oxy}-4-iodobutane

Conditions
ConditionsYield
With sodium iodide In acetonitrile at 55℃; for 16h; Inert atmosphere;100%
With sodium iodide In tetrahydrofuran; acetonitrile at 55℃; for 18h; Inert atmosphere;100%
With sodium iodide In acetonitrile at 20℃; Inert atmosphere; Darkness;93%
(2-furyl)methyl alcohol
98-00-0

(2-furyl)methyl alcohol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-butyl(furan-2-ylmethoxy)dimethylsilane
121389-55-7

tert-butyl(furan-2-ylmethoxy)dimethylsilane

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at -78 - 20℃;100%
With 1H-imidazole In N,N-dimethyl-formamide99%
With 1H-imidazole In N,N-dimethyl-formamide at 23℃; for 0.5h;97%
furan-3-methanol
4412-91-3

furan-3-methanol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-butyl (furan-3-ylmethoxy)dimethylsilane
89861-06-3

tert-butyl (furan-3-ylmethoxy)dimethylsilane

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 2h;100%
With 1H-imidazole In dichloromethane100%
With N-ethyl-N,N-diisopropylamine In dichloromethane for 1h; Ambient temperature;98%
indole
120-72-9

indole

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

N-tert-butyldimethylsilylindole
40899-73-8

N-tert-butyldimethylsilylindole

Conditions
ConditionsYield
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;
100%
Stage #1: indole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h;
100%
Stage #1: indole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.75h; Inert atmosphere;
Stage #2: tert-butyldimethylsilyl chloride In tetrahydrofuran; mineral oil at 0 - 20℃; for 12h; Inert atmosphere;
93%
pyridine-4-methanol
586-95-8

pyridine-4-methanol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

4-((tert-butyldimethylsilyloxy)methyl)pyridine
117423-41-3

4-((tert-butyldimethylsilyloxy)methyl)pyridine

Conditions
ConditionsYield
With 1H-imidazole In DMF (N,N-dimethyl-formamide) for 3.25h;100%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;100%
Stage #1: tert-butyldimethylsilyl chloride With 1H-imidazole In dichloromethane; N,N-dimethyl-formamide for 0.166667h; Inert atmosphere;
Stage #2: pyridine-4-methanol In dichloromethane; N,N-dimethyl-formamide at 20℃; for 13h; Inert atmosphere;
99%
5-hydroxymethyl-2-furfuraldehyde
67-47-0

5-hydroxymethyl-2-furfuraldehyde

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

5-(((tert-butyldimethylsilyl)oxy)methyl)furan-2-carbaldehyde
155108-06-8

5-(((tert-butyldimethylsilyl)oxy)methyl)furan-2-carbaldehyde

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 24h; Inert atmosphere;100%
Stage #1: 5-hydroxymethyl-2-furfuraldehyde With 1H-imidazole In dichloromethane at 20℃; for 0.25h; Inert atmosphere;
Stage #2: tert-butyldimethylsilyl chloride In dichloromethane at 20℃; Inert atmosphere; Darkness;
99%
With potassium carbonate In dichloromethane at 20℃; for 12h;99%
1,3-dihydroxyacetone dimer
62147-49-3

1,3-dihydroxyacetone dimer

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1,3-bis-O-(tert-butyldimethylsilyl)-1,3-dihydroxy-2-propanone
127382-65-4

1,3-bis-O-(tert-butyldimethylsilyl)-1,3-dihydroxy-2-propanone

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 18h;100%
With triethylamine In dichloromethane at 20℃; for 12h;99%
With 1H-imidazole In N,N-dimethyl-formamide for 3h; Ambient temperature;98%
2-(3-indole)-ethanol
526-55-6

2-(3-indole)-ethanol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3-(2-((tert-butyldimethylsilyl)oxy)ethyl)-1H-indole
101079-48-5

3-(2-((tert-butyldimethylsilyl)oxy)ethyl)-1H-indole

Conditions
ConditionsYield
With 1H-imidazole In tetrahydrofuran at 0 - 20℃; for 0.5h; Inert atmosphere;100%
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;100%
With 1H-imidazole In N,N-dimethyl-formamide for 16h; Ambient temperature;99%
7-hydroxychroman-2-one
5631-67-4

7-hydroxychroman-2-one

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

7-((tert-butyldimethylsilyl)oxy)chroman-2-one
82861-23-2

7-((tert-butyldimethylsilyl)oxy)chroman-2-one

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 25℃; for 10h;100%
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;91%
2'-deoxyuridine
951-78-0

2'-deoxyuridine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3',5'-O-di(tert-butyldimethylsilyl)-2'-deoxyuridine
64911-18-8

3',5'-O-di(tert-butyldimethylsilyl)-2'-deoxyuridine

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 50℃; for 3h;100%
With pyridine; 1H-imidazole at 0 - 20℃;100%
With 1H-imidazole In N,N-dimethyl-formamide Etherification;97%
5-bromo-2'-deoxyuridine
59-14-3

5-bromo-2'-deoxyuridine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3',5'-di-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine
154925-95-8

3',5'-di-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine

Conditions
ConditionsYield
With pyridine at 40℃; for 20h; Inert atmosphere;100%
With 1H-imidazole; dmap In N,N-dimethyl-formamide at 20℃; for 12h;99%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 60h;96%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1.5h;94%
With TEA In tetrahydrofuran at 75℃; for 40h;65%
lithium cyanide
2408-36-8

lithium cyanide

cyclohexanone
108-94-1

cyclohexanone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

1-<(tert-butyldimethylsilyl)oxy>-1-cyanocyclohexane
114114-74-8

1-<(tert-butyldimethylsilyl)oxy>-1-cyanocyclohexane

Conditions
ConditionsYield
In tetrahydrofuran for 70h; Ambient temperature;100%
2'-Deoxyguanosine
961-07-9

2'-Deoxyguanosine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine
51549-35-0

3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;100%
With 1H-imidazole In N,N-dimethyl-formamide silylation;97%
With 1H-imidazole In N,N-dimethyl-formamide; toluene for 3h; Inert atmosphere; Heating; Large scale;97%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

p-[(tert-butyldimethylsilyl)oxy]benzaldehyde
120743-99-9

p-[(tert-butyldimethylsilyl)oxy]benzaldehyde

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran100%
With dmap; triethylamine In [D3]acetonitrile at 25℃; for 0.2h;99%
With triethylamine In dichloromethane at 20℃; for 2h;98%
salicylaldehyde
90-02-8

salicylaldehyde

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-((tert-butyldimethylsilyl)oxy)benzaldehyde
116585-12-7

2-((tert-butyldimethylsilyl)oxy)benzaldehyde

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 1h;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 12h; Schlenk technique; Glovebox;100%
vanillin
121-33-5

vanillin

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

O-tert-butyldimethylsilylvanillin
69404-94-0

O-tert-butyldimethylsilylvanillin

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 2h;100%
With 1H-imidazole; dmap In dichloromethane at 20℃; Inert atmosphere;100%
With 1H-imidazole; dmap In dichloromethane at 20℃; for 2h;100%
ethylene glycol
107-21-1

ethylene glycol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-(tert-butyldimethylsilyloxy)ethanol
102229-10-7

2-(tert-butyldimethylsilyloxy)ethanol

Conditions
ConditionsYield
With triethylamine In dichloromethane for 0.166667h; Cooling with ice;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃;99%
With pyridine at 20℃; for 2h; Inert atmosphere;99%
isovanillin
621-59-0

isovanillin

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde
97315-18-9

p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; N,N-dimethyl-formamide at 20℃;100%
With 2-(Dimethylamino)pyridine; triethylamine In dichloromethane at 0 - 20℃; for 12h;100%
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran; N,N-dimethyl-formamide Inert atmosphere;100%
ethyl 2-hydroxypropionate
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(S)-(-)-ethyl 2-(tert-butyldimethylsilyloxy)propanoate
105198-38-7

(S)-(-)-ethyl 2-(tert-butyldimethylsilyloxy)propanoate

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane a) RT, overnight, b) reflux, 10 h;100%
With 1H-imidazole
With 1H-imidazole In dichloromethane Ambient temperature;
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 12h;
5-Hexen-1-ol
821-41-0

5-Hexen-1-ol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-butyl(5-hexenyloxy)dimethylsilane
85807-84-7

tert-butyl(5-hexenyloxy)dimethylsilane

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide100%
With 1H-imidazole In tetrahydrofuran at 20℃;100%
With 1H-imidazole In dichloromethane at 20℃; for 19h;100%
6-Hydroxyhexanoic acid
1191-25-9

6-Hydroxyhexanoic acid

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

6-(tert-butyldimethylsilyloxy)hexanoic acid
77744-44-6

6-(tert-butyldimethylsilyloxy)hexanoic acid

Conditions
ConditionsYield
Stage #1: 6-Hydroxyhexanoic acid With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: tert-butyldimethylsilyl chloride In N,N-dimethyl-formamide at 20℃; for 0.5h;
100%
With 1H-imidazole In N,N-dimethyl-formamide at 25℃; for 0.25h;87%
With 1H-imidazole In N,N-dimethyl-formamide at 50℃; Inert atmosphere;86%
With 1H-imidazole In N,N-dimethyl-formamide at 50℃;80%
With 1H-imidazole In N,N-dimethyl-formamide at 50℃; Inert atmosphere;
2,3-O-isopropylidene-L-threitol
50622-09-8

2,3-O-isopropylidene-L-threitol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

[(4S,5S)-5-[(tert-butyl(dimethyl)silyl)oxymethyl]-2,2-dimethyl-1,3-dioxolan-4-yl]methanol
108817-96-5

[(4S,5S)-5-[(tert-butyl(dimethyl)silyl)oxymethyl]-2,2-dimethyl-1,3-dioxolan-4-yl]methanol

Conditions
ConditionsYield
Stage #1: 2,3-O-isopropylidene-L-threitol With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: tert-butyldimethylsilyl chloride In tetrahydrofuran at 20℃; for 16h;
100%
With 1H-imidazole; dmap In dichloromethane at 20℃; for 3h; Inert atmosphere;100%
Stage #1: 2,3-O-isopropylidene-L-threitol With sodium hydride In tetrahydrofuran at 20℃; for 0.75h; Inert atmosphere;
Stage #2: tert-butyldimethylsilyl chloride In tetrahydrofuran at 20℃; for 0.75h; Inert atmosphere;
98%
p-cresol
106-44-5

p-cresol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

tert-Butyl(dimethyl)-(4-methylphenoxy)silane
62790-85-6

tert-Butyl(dimethyl)-(4-methylphenoxy)silane

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide100%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 16h;99%
With 1H-imidazole; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 20℃; for 2h;97%
4-Fluorophenol
371-41-5

4-Fluorophenol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

4-<(dimethyl-tert-butylsilyl)oxy>fluorobenzene
113984-68-2

4-<(dimethyl-tert-butylsilyl)oxy>fluorobenzene

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;100%
With 1H-imidazole In N,N-dimethyl-formamide at 25℃; for 12h;98%
With 1H-imidazole In N,N-dimethyl-formamide at 0℃; for 1h;91%
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