216755-57-6

Basic information

• Product Name: 3-Fluoro-5-bromobenzyl bromide
• Synonyms: 3-Fluoro-5-bromobenzyl bromide;5-bromo-3-fluorobenzyl bromide;1-Bromo-3-(bromomethyl)-5-fluorobenzene;3-Fluoro-5-broMobenl broMide;1-Bromo-3-(bromomethyl)-5-fluorobenzene, alpha,3-Dibromo-5-fluorotoluene;3-Fluoro-5-bromoben bromide
• CAS NO: 216755-57-6
• Molecular Formula: C₇H₅Br₂F
• Molecular Weight: 267.93
• Product Categories: Fluorine series;alkyl bromide| alkyl Fluorine
• Mol File: 216755-57-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 47 °C
• Boiling Point: 251℃
• Flash Point: 106℃
• Appearance: /
• Density: 1.923
• Vapor Pressure: 0.033mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: soluble in Methanol
• Water Solubility: Slightly soluble in water (2.9 g/L) (25°C).
• Sensitive: Lachrymatory
• CAS DataBase Reference: 3-Fluoro-5-bromobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-5-bromobenzyl bromide(216755-57-6)
• EPA Substance Registry System: 3-Fluoro-5-bromobenzyl bromide(216755-57-6)

Safety Data

• Hazard Codes: C,T
• Statements: 25
• Safety Statements: 45
• HazardClass: 8
• Hazardous Substances Data: 216755-57-6(Hazardous Substances Data)

Usage

Description

3-Fluoro-5-bromobenzyl bromide is an organic compound characterized by the presence of a fluorine atom at the 3-position and a bromine atom at the 5-position on a benzene ring. It also features a bromine atom attached to the benzyl group, which is a phenylmethyl moiety. 3-Fluoro-5-bromobenzyl bromide is known for its potential reactivity and versatility in chemical synthesis, making it a valuable building block in various applications.

Uses

Used in Pharmaceutical Industry:
3-Fluoro-5-bromobenzyl bromide is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Research:
In the field of chemical research, 3-Fluoro-5-bromobenzyl bromide serves as a valuable intermediate for the preparation of a wide range of organic compounds. Its reactivity and the presence of both electron-withdrawing and electron-donating groups make it suitable for various synthetic routes, including cross-coupling reactions, nucleophilic substitutions, and electrophilic aromatic substitutions.
These applications highlight the importance of 3-Fluoro-5-bromobenzyl bromide as a versatile intermediate in both the pharmaceutical and chemical research industries, where its unique structural features contribute to the development of novel and effective compounds.

InChI:InChI=1/C7H5Br2F/c8-4-5-1-6(9)3-7(10)2-5/h1-3H,4H2

Upstream product

• 216755-56-5 5-fluoro-3-hydroxymethylbromobenzene 
• 176548-70-2 3-bromo-5-fluorobenzoic acid 
• 202865-83-6 1-bromo-3-fluoro-5-methylbenzene 

Downstream Products

• 954124-37-9 tert-butyl 4-((3-bromo-5-fluorobenzyloxy)methyl)-4-phenylpiperidine-1-carboxylate 
• 887969-58-6 C₁₆H₂₁BrFNO₄ 
• 947250-98-8 C₃₀H₄₀F₂N₂O₆ 
• 947251-09-4 C₂₉H₃₈F₂N₂O₆ 
• 305800-58-2 2-[3-bromo-5-fluorophenyl]acetonitrile 
• 216755-11-2 N-(4-tert-butylbenzyl)-N-methyl-(3-bromo-5-fluorobenzyl)amine 
• 1192039-98-7 tert-butyl 1-(3-bromo-5-fluorobenzyl)-cyclopropanecarboxylate 
• 1192040-04-2 tert-butyl 1-[3-(benzylamino)-5-fluorobenzyl]-cyclopropanecarboxylate 
• 1192040-10-0 tert-butyl 1-(3-amino-5-fluorobenzyl)-cyclopropanecarboxylate 
• 1331750-45-8 tert-butyl 2-(N-(3-bromo-5-fluorobenzyl)-2,2-dimethylchroman-6-sulfonamido)acetate 
• 1620084-30-1 (2S,5R)-2-(3-bromo-5-fluorobenzyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazine 
• 1620084-31-2 (S)-methyl 2-amino-3-(3-bromo-5-fluorophenyl)propanoate hydrochloride 
• 1620084-32-3 (S)-tert-butyl 2-allyl-3-(2-(3-(3-bromo-5-fluorophenyl)-1-methoxy-1-oxopropan-2-ylamino)-2-oxoethyl)-1H-indole-1-carboxylate 

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