221040-07-9

Basic information

• Product Name: 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE
• Synonyms: 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE;4-Benzyloxy-2-fluoro-1-nitrobenzene 98%;4-Benzyloxy-2-fluoro-1-nitrobenzene98%
• CAS NO: 221040-07-9
• Molecular Formula: C₁₃H₁₀FNO₃
• Molecular Weight: 247.2218032
• Product Categories: blocks;FluoroCompounds;NitroCompounds
• Mol File: 221040-07-9.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 385.3°Cat760mmHg
• Flash Point: 186.8°C
• Appearance: /
• Density: 1.299g/cm³
• CAS DataBase Reference: 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE(221040-07-9)
• EPA Substance Registry System: 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE(221040-07-9)

Safety Data

• Hazard Codes: Xi,C
• Statements: 34
• Safety Statements: 36/37-45
• Hazardous Substances Data: 221040-07-9(Hazardous Substances Data)

Usage

General Description

4-BENZYLOXY-2-FLUORO-1-NITROBENZENE is a chemical compound with the molecular formula C13H10FNO3. It is an aromatic compound that contains a benzene ring with a benzyloxy group, a fluorine atom, and a nitro group attached. 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE is commonly used in organic synthesis and pharmaceutical research due to its potential as a building block for creating more complex molecules. It is also used as an intermediate in the production of various pharmaceuticals and agrochemicals. Additionally, 4-BENZYLOXY-2-FLUORO-1-NITROBENZENE has been studied for its potential biological activities and is considered an important tool for medicinal chemistry research.

Upstream product

• 394-41-2 3-fluoro-4-nitrophenol 
• 100-39-0 benzyl bromide 
• 311-28-4 tetra-(n-butyl)ammonium iodide 
• 446-35-5 2,4-Difluoronitrobenzene 
• 100-51-6 benzyl alcohol 

Downstream Products

• 221040-10-4 N-(5-benzyloxy-2-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline 
• 221040-11-5 N-(5-benzyloxy-2-nitrophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 496837-94-6 5-(benzyloxy)-N-methyl-2-nitroaniline 
• 496837-95-7 5-(benzyloxy)-N₁-methylbenzene-1,2-diamine 
• 496838-02-9 N-(6-benzyloxy-1-methyl-1H-benzoimidazol-2-yl)-benzamide 
• 221040-21-7 5,6-dihydro-9-benzyloxybenzimidazo<2,1-a>isoquinoline 
• 221040-14-8 5,6-dihydro-9-benzyloxybenzimidazo<2,1-a>isoquinoline N-oxide 
• 221040-22-8 9-benzyloxy-5,6-dihydro-2,3-dimethoxybenzimidazo<2,1-a>isoquinoline 
• 221040-15-9 9-benzyloxy-5,6-dihydro-2,3-dimethoxybenzimidazo<2,1-a>isoquinoline N-oxide 
• 686271-02-3 4-(benzyloxy)-2-(benzylsulfanyl)-1-nitrobenzene 
• 521287-22-9 ethyl 5-benzyloxy-2-nitrophenylcyanoacetate 
• 887757-15-5 3-[5-(benzyloxy)-2-nitroanilino]butanoic acid 
• 1002727-67-4 2-(5-Benzyloxy-2-nitro-phenoxymethyl)-2-methyl-oxirane 
• 1232234-79-5 2-(5-benzyloxy-2-nitro-phenylamino)-4-(3-chloro-phenyl)-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Compound of formula (I): wherein A1, A2, Ra, Rb, Rc, Rd, R3, R4, X, Y and G are as defined in the description, and their use in the manufacture of medicaments.

PHENYLACETAMIDES AS INHIBITORS OF ROCK

The present invention provides compounds of Formula (I): Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

NOVEL MEDICINE COMPOSED OF BENZIMIDAZOLE COMPOUND

PROBLEM TO BE SOLVED: To provide an agent for treating or preventing a disease associated with SCN9A(Nav1.7). SOLUTION: The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. [R1a, R1b, R1c, R1d: H, halogen, cyano, C1-4 alkyl, C1-4 alkoxy or the like. R2, R3: H, C1-6 alkyl, C3-10 cycloalkyl or the like. R4: H, C1-6 alkyl, C3-7 cycloalkyl or the like. m: 1, 2 or 3. L: CR7R8(R7, R8: H, OH, C1-4 alkyl, C1-4 alkoxy or the like)]. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT