22571-78-4Relevant articles and documents
Ozonolysis of verbenone in aprotic solvents
Kukovinets, Olga S.,Zvereva, Tatyana I.,Kabalnova, Natalya N.,Kasradze, Vakhtang G.,Salimova, Elena V.,Khalitova, Lyucia R.,Abdullin, Marat I.,Spirikhin, Leonid V.
, p. 106 - 107 (2009)
The ozonolysis of verbenone in methylene chloride and acetonitrile at -60 and 0 °C proceeds with cleavage of the double bond and neighbouring σ-bond to give (1R,3S)-acetyl-2,2-dimethylcyclobutane carboxylic acid. The mechanism of the reaction has been pro
NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS
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Paragraph 212, (2014/07/21)
The invention relates to novel betulinic acid derivatives and related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases. These compounds are esterified in position 3 and are substituted in position 17 of the betulinic acid structure, via a linking group W, by a saturated 5-7 membered nitrogen-heterocycle.
AMINOPYRIMIDINES AS SYK INHIBITORS
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Page/Page column 39-40, (2012/12/13)
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.