22614-69-3 Usage
Description
8-Methoxyquinolin-2(1H)-one is an organic compound with the molecular formula C10H9NO2. It is a derivative of quinolinone, featuring a methoxy group at the 8th position and a ketone group at the 2nd position. 8-Methoxyquinolin-2(1H)-one is known for its potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
8-Methoxyquinolin-2(1H)-one is used as an intermediate in the synthesis of metabolites for [application reason] in the treatment of asthma. Specifically, it is involved in the synthesis of procaterol hydrochloride (Meptin), a β2-adrenergic agonist that helps in managing asthma symptoms by relaxing the muscles in the airways and increasing airflow to the lungs.
Please note that the provided materials only mention the use of 8-Methoxyquinolin-2(1H)-one as an intermediate in the synthesis of metabolites for a specific pharmaceutical application. If there are other uses or applications in different industries, additional information would be required to list them.
Check Digit Verification of cas no
The CAS Registry Mumber 22614-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,6,1 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 22614-69:
(7*2)+(6*2)+(5*6)+(4*1)+(3*4)+(2*6)+(1*9)=93
93 % 10 = 3
So 22614-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO2/c1-13-8-4-2-3-7-5-6-9(12)11-10(7)8/h2-6H,1H3,(H,11,12)
22614-69-3Relevant articles and documents
Efficient visible light mediated synthesis of quinolin-2(1H)-ones from quinolineN-oxides
Bhuyan, Samuzal,Chhetri, Karan,Hossain, Jagir,Jana, Saibal,Mandal, Susanta,Roy, Biswajit Gopal
, p. 5049 - 5055 (2021/07/29)
Quinolin-2(1H)-ones are one of the important classes of compounds due to their prevalence in natural products and in pharmacologically useful compounds. Here we present an unconventional and hitherto unknown photocatalytic approach to their synthesis from easily available quinoline-N-oxides. This reagent free highly atom economical photocatalytic method, with low catalyst loading, high yield and no undesirable by-product, provides an efficient greener alternative to all conventional synthesis reported to date. The robustness of the methodology has been successfully demonstrated with easy scaling up to the gram scale.
DEOXYURIDINE TRIPHOSPHATASE INHIBITORS
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Paragraph 0269, (2014/07/22)
Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
Regioselectivity of the metalation of polymethoxylated pivaloyl-aminobenzenes. Synthesis of methoxy-2(1H)-quinolones. Precursors of 2-substituted-5,8-quinolinediones
Fourquez,Godard,Marsais,Queguiner
, p. 1165 - 1170 (2007/10/02)
Synthesis of methoxy-2(1H)-quinolones precursors of 2-substituted-5,8-quinolinediones is described. A metalation, Heck coupling reaction and cyclisation sequence is used. Regioselectivity of the metalation of methoxypivaloylaminobenzenes is studied.