23091-35-2Relevant articles and documents
Synthesis of Structurally Diverse Benzotriazoles via Rapid Diazotization and Intramolecular Cyclization of 1,2-Aryldiamines
Faggyas, Réka J.,Sloan, Nikki L.,Buijs, Ned,Sutherland, Andrew
supporting information, p. 5344 - 5353 (2019/05/21)
An operationally simple method has been developed for the preparation of N-unsubstituted benzotriazoles by diazotization and intramolecular cyclization of a wide range of 1,2-aryldiamines under mild conditions, using a polymer-supported nitrite reagent and p-tosic acid. The functional group tolerance of this approach was further demonstrated with effective activation and cyclization of N-alkyl, -aryl, and -acyl ortho-aminoanilines leading to the synthesis of N1-substituted benzotriazoles. The synthetic utility of this one-pot heterocyclization process was exemplified with the preparation of a number of biologically and medicinally important benzotriazole scaffolds, including an α-amino acid analogue.
Microwave-assisted reductive cyclization of N-allyl 2-nitroanilines: A new approach to substituted 1,2,3,4-tetrahydroquinoxalines
Merisor, Elena,Conrad, Jürgen,Mika, Sabine,Beifuss, Uwe
, p. 2033 - 2036 (2008/02/09)
N-Allyl 2-nitrophenyl amines can be efficiently cyclized to yield alkenyl-1,2,3,4-tetrahydroquinoxalines in a single reaction step by means of a new microwave-assisted reductive domino process. Georg Thieme Verlag Stuttgart.
Process for producing N-acylnitroaniline derivative
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, (2008/06/13)
A process of reacting a nitroaniline compound of formula (2); with acid anhydride or acid chloride is carried out in the presence of an alkali metal compound or an alkaline earth metal compound to produce acylnitroaniline derivative. The process further includes the step of reacting the resulting product with a compound of formula (5); R2—Y ??(5) to produce an N-acylnitroaniline derivative of formula (1);