244298-89-3

Basic information

• Product Name: (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(3,4-dimethoxyphenyl)methanone
• Synonyms: (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(3,4-dimethoxyphenyl)methanone
• CAS NO: 244298-89-3
• Molecular Weight: 317.409
• Mol File: 244298-89-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(3,4-dimethoxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(3,4-dimethoxyphenyl)methanone(244298-89-3)
• EPA Substance Registry System: (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(3,4-dimethoxyphenyl)methanone(244298-89-3)

Safety Data

• Hazardous Substances Data: 244298-89-3(Hazardous Substances Data)

Upstream product

• 4640-69-1 ω-cyano-3,4-dimethoxyacetophenone 
• 108-94-1 cyclohexanone 

Downstream Products

• 244298-90-6 N-[3-(3,4-dimethoxybenzoyl)-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl]acetonitrile 
• 244298-87-1 2-chloromethyl-4-(3,4-dimethoxy-phenyl)-benzo[4,5]thieno[2,3-b]pyridine-3-carboxylic acid ethyl ester 
• 244298-91-7 N-[3-(3,4-dimethoxybenzoyl)-benzo[b]thiophen-2-yl]acetamide 
• 244298-92-8 2-amino-3-(3,4-dimethoxybenzoyl)benzo[b]thiophene 

Relevant articles and documents

THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS

The present invention relates to a series of compounds of formula (A) having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.

Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles

A new series of compounds, in which the 2-amino-4-methoxyphenyl ring of phenstatin analogue 5 was replaced with 2- or 3-amino-benzoheterocycles, was synthesized and evaluated for antiproliferative activity and inhibition of colchicine binding. The lack of