244298-90-6Relevant articles and documents
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization
Romagnoli, Romeo,Baraldi, Pier Giovanni,Carrion, Maria Dora,Cara, Carlota Lopez,Preti, Delia,Fruttarolo, Francesca,Pavani, Maria Giovanna,Tabrizi, Mojgan Aghazadeh,Tolomeo, Manlio,Grimaudo, Stefania,Di Cristina, Antonella,Balzarini, Jan,Hadfield, John A.,Brancale, Andrea,Hamel, Ernest
, p. 2273 - 2277 (2008/02/02)
Two new series of inhibitors of tubulin polymerization based on the 2-amino-3-(3,4,5-trimethoxybenzoyl)-benzo[b]thiophene molecular skeleton and its 3-amino positional isomer were synthesized and evaluated for antiproliferative activity, inhibition of tub
Studies on disease-modifying antirheumatic drugs. IV. Synthesis of novel thieno[2,3-b : 5,4-c']dipyridine derivatives and their anti-inflammatory effect
Baba, Atsuo,Mori, Akira,Yasuma, Tsuneo,Unno, Satoko,Makino, Haruhiko,Sohda, Takashi
, p. 993 - 999 (2007/10/03)
The syntheses and anti-inflammatory activities of novel thieno[2,3- b]pyridine and thieno[2,3-b:5,4-c']-dipyridine derivatives are described. These compounds were designed by modification of the quinoline template of a new type of disease-modifying antirh