25004-95-9 Usage
Description
Trichloromethanesulfinyl Chloride, also known as Tosyl Chloride (TsCl), is an organic compound with the chemical formula Cl3C-SO2Cl. It is a colorless to pale yellow liquid that is soluble in organic solvents and is widely used in organic synthesis due to its reactivity and versatility.
Uses
Used in Organic Synthesis:
Trichloromethanesulfinyl Chloride is used as a reactant for the one-pot synthesis of allenecarboxylates. This application takes advantage of its reactivity as a chlorosulfonylating agent, enabling the formation of various organic compounds with potential applications in pharmaceuticals, agrochemicals, and materials science.
If there are additional applications in different industries, they can be listed as follows:
Used in Pharmaceutical Industry:
Trichloromethanesulfinyl Chloride is used as a protecting group agent for alcohols and amines in the synthesis of complex organic molecules, such as drugs and biologically active compounds. Its ability to selectively protect functional groups during multi-step synthesis processes is crucial for the successful development of new pharmaceuticals.
Used in Chemical Research:
In the field of chemical research, Trichloromethanesulfinyl Chloride is employed as a reagent for the introduction of the tosyl (Ts) group, which can be used to modify the reactivity and selectivity of various organic substrates. This modification can be useful for studying reaction mechanisms, understanding structure-activity relationships, and developing new synthetic methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 25004-95-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,0,0 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25004-95:
(7*2)+(6*5)+(5*0)+(4*0)+(3*4)+(2*9)+(1*5)=79
79 % 10 = 9
So 25004-95-9 is a valid CAS Registry Number.
InChI:InChI=1/CCl4OS/c2-1(3,4)7(5)6
25004-95-9Relevant articles and documents
Preparation method of trifluoromethylsulfinyl halide (by machine translation)
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Paragraph 0029-0043, (2020/04/22)
The invention relates to a trifluoromethylsulfinyl halide (chemical formula of F. 3 Process CSOX) of, This compound is used as a pesticide, for the preparation of pesticides and fine chemicals, in particular for preparing insecticide fipronil, and its preparation process :1) trichloromethyl thionyl chloride, i.e. Cl3 Reaction of CSCl with oxidant gives trichloromethyl sulfinyl chloride, (Cl)3 CSOCl;2) Trichloromethyl sulfinyl chloride Cl3 Reaction of CSOCl) with fluoride to give trifluoromethanesulphonyl halide, i.e. F3 CSOX. Has the advantage: that the preparation of trifluoromethylsulfinyl halide avoids the low boiling, highly toxic starting materials and intermediates, namely trifluoromethyl sulfachloride and di (trifluoromethyl) bisulfide, has the advantages, of simple, efficient, safe; convenience and the like, and uses cheap and readily available raw material trichloromethyl sulfur chloride or a mixture, thereof to reduce manufacturing cost. (by machine translation)
Reactions of N-Sulfinyl Compounds, XV. - Synthesis of 2-Alkenesulfinic Acid Amides - Structure-Reactivity Relationships for N-Sulfinyl Compounds as Enophiles
Bussas, Reinhard,Kresze, Guenter
, p. 545 - 563 (2007/10/02)
The reactivity of N-sulfinyl compounds R6NSO 2 in ene-reactions shows a large variation depending on the nature of the group R6.Haloalkanesulfonamide derivatives react even with very unreactive alkenes.The scope of this method for the synthesis of sulfinic acid amides and the side reactions are discussed.