2519-61-1 Usage
Description
4-Chloroindole-3-acetic acid is an organic compound with the chemical formula C10H8ClNO2. It is an off-white solid and is known for its potential applications in various fields due to its unique chemical properties.
Uses
Used in Plant Growth Stimulation:
4-Chloroindole-3-acetic acid is used as a plant growth stimulator for promoting the growth and development of plants. It enhances the rooting process, leading to stronger and healthier plants.
Used in New Rooting Promoters:
4-Chloroindole-3-acetic acid is used as a new rooting promoter in the agricultural industry. It is a potent candidate for developing new rooting promoters without estrogenic activity, making it a safer and more effective option for plant propagation.
Used in Pharmaceutical Research:
4-Chloroindole-3-acetic acid, due to its unique chemical structure, can be used as a starting material or intermediate in the synthesis of various pharmaceutical compounds. Its potential applications in drug discovery and development are currently being explored by researchers.
Used in Chemical Synthesis:
As an off-white solid with specific chemical properties, 4-Chloroindole-3-acetic acid can be utilized in various chemical synthesis processes. It can serve as a building block for the creation of more complex molecules with specific applications in different industries.
Used in Research and Development:
4-Chloroindole-3-acetic acid is used in research and development for studying its properties and potential applications. Scientists and researchers can use this compound to gain insights into its behavior and reactivity, which can lead to the discovery of new applications and uses in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 2519-61-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,1 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2519-61:
(6*2)+(5*5)+(4*1)+(3*9)+(2*6)+(1*1)=81
81 % 10 = 1
So 2519-61-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H8ClNO2/c11-7-2-1-3-8-10(7)6(5-12-8)4-9(13)14/h1-3,5,12H,4H2,(H,13,14)
2519-61-1Relevant articles and documents
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Hansch,Godfrey
, p. 3518 (1951)
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A 4 - chloro indole - 3 - acetic acid
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, (2018/04/20)
The invention discloses a 4-chloroindole-3-acetic acid preparing method. The method specifically comprises the steps of 1, conducting condensation reaction of a compound i and DMFDMA at the temperature of 80-120 DEG C in anhydrous DMF solvent, so that a compound ii is generated; 2, dissolving the compound ii in solvent formed by mixing THF with alcohol, adding Raney nickel and adding hydrazine hydrate dropwise for reaction at the temperature of 15-30 DEG C in an inert atmosphere, and obtaining a compound iii after reaction ends completely; 3, dissolving the compound iii in solvent, adding inorganic strong base and a phase transfer catalyst, adding a compound iv dropwise at the temperature of 20-35 DEG C for substitution reaction, conducting heating for backflow after the compound iv is added, and obtaining a compound v after reaction ends completely; 4, hydrolyzing the compound v to obtain the target product 4-chloroindole-3-acetic acid. According to the preparing method, no highly-toxic product is adopted as raw materials, and the whole reaction process is safe.
Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy
Rossiter, Sharon,Folkes, Lisa K.,Wardman, Peter
, p. 2523 - 2526 (2007/10/03)
Substituted indole-3-acetic acid (IAA) derivatives, plant auxins with potential for use as prodrugs in enzyme-prodrug directed cancer therapies, were oxidised with horseradish peroxidase (HRP) and toxicity against V79 Chinese hamster lung fibroblasts was determined. Rate constants for oxidation by HRP compound I were also measured. Halogenated IAAs were found to be the most cytotoxic, with typical surviving fractions of -3 after incubation for 2 h with 100 μM prodrug and HRP.
