267413-25-2 Usage
General Description
5-Aminomethyl indazole is a chemical compound that belongs to the class of indazole derivatives. It is a white powder that is used in various chemical and pharmaceutical applications. 5-Aminomethyl indazole has been studied for its potential role in drug development, particularly in the field of pharmacology and medicinal chemistry. It is known for its ability to act as a building block in the synthesis of various bioactive molecules and pharmaceutical drugs. Additionally, research has shown that 5-aminomethyl indazole exhibits antimicrobial and antitumor activities, making it a potential candidate for the development of new drugs to treat infectious and cancerous diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 267413-25-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,7,4,1 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 267413-25:
(8*2)+(7*6)+(6*7)+(5*4)+(4*1)+(3*3)+(2*2)+(1*5)=142
142 % 10 = 2
So 267413-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H9N3/c9-4-6-1-2-8-7(3-6)5-10-11-8/h1-3,5H,4,9H2,(H,10,11)
267413-25-2Relevant articles and documents
FUSED HETEROCYCLIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS
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Page/Page column 18; 33, (2010/05/13)
The present invention is directed to fused heterocyclic compounds of formula (I): which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schi
Discovery of N-[(1-aryl-1H-indazol-5-yl)methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathway
Dessole, Gabriella,Branca, Danila,Ferrigno, Federica,Kinzel, Olaf,Muraglia, Ester,Palumbi, Maria Cecilia,Rowley, Michael,Serafini, Sergio,Steinkuehler, Christian,Jones, Philip
experimental part, p. 4191 - 4195 (2010/04/24)
We report the synthesis and biological evaluation of N-[(1-aryl-1H-indazol-5-yl)methyl]amide derivatives as Smoothened antagonists and inhibitors of the Hedgehog pathway. Identification of the lead structure 1 by HTS, followed by SAR study on the amide and aryl portions led to the discovery of antagonists with nanomolar activity.
Rho KINASE INHIBITORS
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Page 56, (2010/02/06)
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