26956-43-4

Basic information

• Product Name: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
• Synonyms: FURO[3,2-C]PYRIDIN-4(5H)-ONE;4-OXO-4,5-DIHYDROFURO[3,2-C]PYRIDINE;4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE;4,5-Dihyro-4-Oxofuro[3,2]Pyridine;4H,5H-furo[3,2-c]pyridin-4-one;Furo[3,2-c]pyridin-4-ol;5H-Furo[3,2-c]pyridin-4-one
• CAS NO: 26956-43-4
• Molecular Formula: C₇H₅NO₂
• Molecular Weight: 135.12
• EINECS: 125-856-9
• Product Categories: Fused Ring Systems
• Mol File: 26956-43-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 202-204 °C
• Boiling Point: 372.805 °C at 760 mmHg
• Flash Point: 179.266 °C
• Appearance: /
• Density: 1.288 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.11±0.20(Predicted)
• CAS DataBase Reference: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE(26956-43-4)
• EPA Substance Registry System: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE(26956-43-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 26956-43-4(Hazardous Substances Data)

Usage

General Description

4,5-Dihydro-4-oxofuro[3,2-c]pyridine is a chemical compound belonging to the furo[3,2-c]pyridine class. It is a heterocyclic compound with a bicyclic structure, containing a furan ring fused to a pyridine ring. 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE is often used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and materials. Its unique structure and reactivity make it valuable in organic synthesis, particularly in the development of new drugs and functional materials. Additionally, research suggests that 4,5-dihydro-4-oxofuro[3,2-c]pyridine derivatives may have potential therapeutic applications, such as antiviral and antibacterial properties. However, further studies are needed to fully understand its biological activities and potential uses.

InChI:InChI=1/C7H5NO2/c9-7-5-2-4-10-6(5)1-3-8-7/h1-4H,(H,8,9)

Upstream product

• 20689-54-7 3-furanylacryloyl chloride 
• 539-47-9 3-(fur-2-yl)crotonic acid 
• 33007-15-7 7-hydroxy-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one 
• 59898-36-1 (E)-3-Furan-2-yl-acryloyl azide 
• 57420-06-1 furo<3,2-c>pyridine N-oxide 
• 108-24-7 acetic anhydride 
• 29080-01-1 β-(2-Furan)-vinylisocyanat 
• 98-01-1 furfural 
• 539-47-9 3-(2-furyl)acrylic acid 
• 46265-05-8 2-(2-amino-1-hydroxy-ethyl)-furan-3-carboxylic acid ethyl ester 
• 119924-26-4 (E)-3-(2-furanyl)-2-propenoyl azide 
• 541-41-3 chloroformic acid ethyl ester 
• 53282-12-5 ethyl (E)-3-(2-furyl)prop-2-enoate 
• 31270-80-1 4-chlorofuro[3,2-c]pyridine 

Downstream Products

• 31270-80-1 4-chlorofuro[3,2-c]pyridine 
• 86518-17-4 formyl-2 dihydro-4,5 oxo-4 furo<3,2-c>pyridine 
• 76312-04-4 4-Bromofuro<3,2-c>pyridin 
• 33007-09-9 furo[3,2-c]pyridin-4-ylamine 
• 603301-02-6 7-bromofuro[3,2-c]pyridine-4(5H)-one 
• 444898-86-6 C₃₃H₂₅NO₉ 
• 799293-73-5 3-bromofuro[3,2-c]pyridin-4-ylamine 
• 799293-74-6 4-amino-3-(4-aminophenyl)-furo[3,2-c]pyridine 
• 799293-76-8 4-amino-3-(4-((2-fluoro-5-(trifluoromethyl)aminocarbonylamino)phenyl))-furo[3,2-c]pyridine 
• 799293-78-0 4-amino-3-(4-((2-fluoro-5-(trifluoromethyl)aminocarbonylamino)phenyl))-7-bromo-furo[3,2-c]pyridine 
• 220939-72-0 4-chloro-3-bromofuro<3,2-c>pyridine 
• 603300-96-5 7-bromofuro[3,2-c]pyridine 
• 603302-91-6 (furo[3,2-c]pyridin-7-yl)methanol 
• 603302-76-7 furo[3,2-c]pyridine-7-carbonitrile 

Relevant articles and documents

Organic metal compound and organic light-emitting device

Organic metal compounds and organic light-emitting devices employing the same are provided. The organic metal compound has a chemical structure of Formula (I) or Formula (II): In particular, one of the following two conditions (1) and (2) is met: (1) R1 is deuterium or C1-6 deuterated alkyl group, when R3 and R4 are independently hydrogen, halogen, C1-6 alkyl group, C1-6 fluoroalkyl or C3-12 heteroaryl group; and (2) R1 is hydrogen, deuterium, C1-6 alkyl group, C1-6 deuterated alkyl group, C3-12 heteroaryl group, or C6-12 aryl group, when at least one of R3 and R4 is C6-12 aryl group or C6-12 fluoroaryl group.

One-pot synthesis of fused 2-pyridones from heteroarylacrylic acid via curtius rearrangement & microwave-assisted thermal electrocyclization

We investigated the one-pot synthesis of several fused 2-pyridone ring systems based on a Curtius rearrangement, followed by a microwave-assisted thermal electrocyclization of a 2-aza-6?-electron system including isocyanate. We synthesized seven heterocyclic compounds containing a fused 2-pyridone ring. In these results, the one-pot synthesis of fused 2-pyridone ring system 5 from (E)-acrylic acids 1 under microwave irradiation conditions was more effective than the conventional reaction conditions in terms of the yield and the reaction time.

IMIDAZOTHIADIAZOLE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION

The present invention provides imidazothiadiazole compounds of Formula (I) wherein A, B, D, Rx, R1, R2, R3, X1, X2 and s are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments.