274673-50-6 Usage
Description
Methyl 2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxylate is a chemical compound with the molecular formula C20H20O2. It belongs to the class of organic compounds known as benzoannulenes, which are polycyclic aromatic compounds containing a benzene ring fused to a cycloheptene ring. This specific compound is an ester, with the methyl group attached to the carboxyl group. Its structural features make it an interesting target for the development of new drugs and materials.
Used in Organic Synthesis:
Methyl 2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxylate is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
Methyl 2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxylate is used as a starting material in the development of new drugs. Its structural features can be modified to create novel compounds with potential therapeutic properties. Researchers can explore its potential as a lead compound for the treatment of various diseases and disorders.
Used in Material Science:
Methyl 2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxylate is used as a component in the development of new materials with unique properties. Its aromatic and cyclic structure can contribute to the formation of materials with enhanced stability, conductivity, or other desirable characteristics.
It is important to handle and use Methyl 2-p-tolyl-6,7-dihydro-5H-benzo[7]annulene-8-carboxylate with caution, as it may have potential health hazards and environmental impacts. Proper safety measures should be taken during its synthesis, storage, and application to minimize any risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 274673-50-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,4,6,7 and 3 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 274673-50:
(8*2)+(7*7)+(6*4)+(5*6)+(4*7)+(3*3)+(2*5)+(1*0)=166
166 % 10 = 6
So 274673-50-6 is a valid CAS Registry Number.
274673-50-6Relevant articles and documents
Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Junker, Anna,Kokornaczyk, Artur K.,Zweemer, Annelien J. M.,Frehland, Bastian,Schepmann, Dirk,Yamaguchi, Junichiro,Itami, Kenichiro,Faust, Andreas,Hermann, Sven,Wagner, Stefan,Sch?fers, Michael,Koch, Michael,Weiss, Christina,Heitman, Laura H.,Kopka, Klaus,Wünsch, Bernhard
supporting information, p. 2407 - 2422 (2015/03/04)
CCR2 and CCR5 receptors play a key role in the development and progression of several inflammatory, cardiovascular and autoimmune diseases. Therefore, dual targeting of both receptors appeals as a promising strategy for the treatment of such complex, mult
Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: Synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety
Shiraishi, Mitsuru,Aramaki, Yoshio,Seto, Masaki,Imoto, Hiroshi,Nishikawa, Youichi,Kanzaki, Naoyuki,Okamoto, Mika,Sawada, Hidekazu,Nishimura, Osamu,Baba, Masanori,Fujino, Masahiko
, p. 2049 - 2063 (2007/10/03)
The search for new small-molecule CCR5 antagonists by high-throughput screening (HTS) of the Takeda chemical library using [125I]RANTES and CHO/CCR5 cells led to the discovery of lead compounds (A, B) with a quaternary ammonium or phosphonium m
