27640-12-6

Basic information

• Product Name: Benzenepropanamine, N,N-diethyl-
• CAS NO: 27640-12-6
• Molecular Formula: C13H21N
• Molecular Weight: 191.316
• Mol File: 27640-12-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenepropanamine, N,N-diethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamine, N,N-diethyl-(27640-12-6)
• EPA Substance Registry System: Benzenepropanamine, N,N-diethyl-(27640-12-6)

Safety Data

• Hazardous Substances Data: 27640-12-6(Hazardous Substances Data)

Upstream product

• 18859-19-3 N,N-diethyl-3-phenylpropanamide 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 109-89-7 diethylamine 
• 536-74-3 phenylacetylene 
• 104-53-0 3-phenyl-propionaldehyde 
• 69804-99-5 3-phenylpropanol methanesulfonate 
• 30076-98-3 (3,3-dimethoxypropyl)benzene 
• 13686-66-3 N,N-diethylaminodimethylsilane 
• 75-09-2 dichloromethane 
• 768-56-9 4-Phenylbut-1-ene 
• 100-35-6 2-(diethylamino)ethyl chloride 
• 6921-34-2 benzylmagnesium chloride 
• 104-52-9 phenylpropyl chloride 

Downstream Products

• 859941-63-2 ethyl-(3-phenyl-propyl)-carbamonitrile 
• 617-83-4 Diethylcyanamide 
• 13125-62-7 1-(ethylamino)-3-phenylpropane 

Relevant articles and documents

Atomically dispersed Rh on hydroxyapatite as an effective catalyst for tandem hydroaminomethylation of olefins

Tandem hydroaminomethylation is an efficient and green route for one-pot synthesis of amines directly from olefins. Herein, heterogeneous hydroxyapatite (HAP) supported single-atom Rh catalyst was prepared and used for tandem hydroaminomethylation of olefins. Characterization techniques confirmed the atomic dispersion of Rh species on HAP. Up to 99% conversion of 1-hexene with high selectivity to the desired amines (93.2%) was obtained over 0.5Rh1/HAP catalyst. Mechanism study demonstrated that the first hydroformylation step during the tandem catalytic process was rate-determining. Compared with the Rh nanoparticles on other oxide supports (Mg3Al, MgO and Al2O3), the atomically dispersed Rh sites on HAP ensured the high hydroformylation activity, thereby guaranteed the outstanding catalytic performance for the total tandem process. Furthermore, various corresponding amines can be obtained with satisfactory yields over 0.5Rh1/HAP catalyst from a wide scope of olefins or amines substrates.

Copper-catalyzed oxygen atom transfer of N-oxides leading to a facile deoxygenation procedure applicable to both heterocyclic and amine N-oxides

Deoxygenation of various types of N-oxides including both heterocyclic and alkyl(aryl)amine derivatives has successfully been developed by the copper-catalyzed oxygen atom transfer using diazo compounds as the oxygen acceptor. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance under mild conditions. This journal is

A convenient and general reduction of amides to amines with low-valent titanium

Low-valent titanium readily prepared in situ from TiCl4 and Mg powder in THF is found to be an active agent for the reduction of amides which were previously considered to be inert towards low-valent titanium. The reaction proceeds under very mild conditions, and is applicable to all types of amides, primary, secondary and tertiary, to produce the corresponding amines in good to excellent yields. This new finding provides a practical, convenient and general method for the important transformation of amides to amines. A plausible reaction mechanism is proposed.