28145-10-0

Basic information

• Product Name: 1-ethyl-3-methyl-urea
• Synonyms: 1-ethyl-3-methyl-urea
• CAS NO: 28145-10-0
• Molecular Formula: C₄H₁₀N₂O
• Molecular Weight: 102.14
• Mol File: 28145-10-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 52-53 °C
• Boiling Point: 267°Cat760mmHg
• Flash Point: 121.6°C
• Appearance: /
• Density: 0.934g/cm³
• Vapor Pressure: 0.00836mmHg at 25°C
• Refractive Index: 1.422
• PKA: 14.89±0.46(Predicted)
• CAS DataBase Reference: 1-ethyl-3-methyl-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethyl-3-methyl-urea(28145-10-0)
• EPA Substance Registry System: 1-ethyl-3-methyl-urea(28145-10-0)

Safety Data

• Hazardous Substances Data: 28145-10-0(Hazardous Substances Data)

Usage

General Description

1-Ethyl-3-methyl-urea is a chemical compound with the molecular formula C5H12N2O. It is a urea derivative and belongs to the class of organic compounds known as ureas. This chemical is a colorless liquid with a boiling point of 209°C and is soluble in water. It is commonly used in industrial applications as a solvent and as a reactant in the production of agricultural chemicals. Additionally, 1-ethyl-3-methyl-urea has been studied for its potential use in medicinal applications, particularly in the treatment of certain types of cancer. However, further research is needed to fully understand its potential pharmaceutical uses.

InChI:InChI=1/C4H10N2O/c1-3-6-4(7)5-2/h3H2,1-2H3,(H2,5,6,7)

Upstream product

• 124-41-4 sodium methylate 
• 80981-26-6 3-Ethyl-1-methyl-1-(1H-pyrazole-4-carbonyl)-urea 
• 80981-24-4 1-Ethyl-3-methyl-1-(1H-pyrazole-4-carbonyl)-urea 
• 39076-43-2 S-methyl N-ethylthiocarbamate 
• 74-89-5 methylamine 
• 593-77-1 N-Methylhydroxylamine 
• 109-90-0 ethyl isocyanate 

Downstream Products

• 41862-13-9 6-amino-1-ethyl-3-methylpyrimidine-2,4(1H,3H)-dione 
• 72479-23-3 C₄H₉N₃O₂ 
• 72479-13-1 N-Methyl-N'-ethyl-N-nitrosourea 
• 1185290-99-6 N-ethyl-N-(methylcarbamoyl)benzamide 
• 1255650-80-6 N-(ethylcarbamoyl)-N-methylbenzamide 

Relevant articles and documents

Microwave-assisted synthesis of symmetrical and unsymmetrical N,N 0-disubstituted thioureas and ureas over MgO in dry media

Under mild microwave irradiation conditions a variety of symmetrical and unsymmetrical A,N′-disubsti-tuted thioureas and ureas were prepared via the reaction of Af-monosubstituted hydroxylamines with isocyanate and isothiocyanate derivatives over MgO under solvent-free conditions. This new method afforded satisfactory results with good yields, short reaction time, and simplicity in the experimental procedure.

Pyrimidine Derivatives and Related Compounds. Part 45. Synthesis of 4-Allophanoylpyrazoles via a Pyrimidine-to-pyrazole Ring Transformation

Reaction of the 5-formyluracil derivatives (1a-f) with hydrazines in the presence of acetic acid produced a ring contraction to give the corresponding 4-allophanoylpyrazoles (2a-h).Further treatment of these pyrazoles (2a-h) with sodium methoxide afforded methyl pyrazole-4-carboxylate (3a).Conceivable mechanisms for the present pyrimidine-to-pyrazole transformation were discussed.