288-35-7

Basic information

• Product Name: 2H-1,2,3-Triazole
• Synonyms: 2,5-Diazapyrrole;Osotriazole
• CAS NO: 288-35-7
• Molecular Formula: C₂H₃N₃
• Molecular Weight: 69.07
• EINECS: 206-022-9
• Mol File: 288-35-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 23.5 °C
• Boiling Point: 203°C at 760 mmHg
• Flash Point: 100.7°C
• Appearance: /
• Density: 1.274g/cm³
• Vapor Pressure: 0.404mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.73±0.70(Predicted)
• CAS DataBase Reference: 2H-1,2,3-Triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2,3-Triazole(288-35-7)
• EPA Substance Registry System: 2H-1,2,3-Triazole(288-35-7)

Safety Data

• Hazardous Substances Data: 288-35-7(Hazardous Substances Data)

Usage

General Description

2H-1,2,3-Triazole is a chemical compound with the molecular formula C2H3N3. It is a five-membered ring compound containing two carbon atoms and three nitrogen atoms. 2H-1,2,3-Triazole is a versatile building block in organic synthesis and is used in the production of pharmaceuticals, agrochemicals, and materials. It is also found in some natural products and has potential biological activities, making it a target for drug discovery and development. Its unique structure and reactivity make it a valuable compound in the field of chemical research and development.

InChI:InChI=1/C2H3N3/c1-2-4-5-3-1/h1-2H,(H,3,4,5)

Upstream product

• 288-36-8 1,2,3-triazole 
• 61177-95-5 3-amino-1,2,4-triazine 2-oxide 
• 64-02-8 disodium ethylenediamine tetraacetic acid 
• 536-74-3 phenylacetylene 

Downstream Products

• 10261-02-6 2-(2-nitro-phenyl)-2H-[1,2,3]triazole 
• 10560-92-6 1-(2-nitrophenyl)-1H-1,2,3-triazole 
• 1628-89-3 2-methoxypyridine 
• 153653-01-1 2-(1,2,3-triazol-2-yl)pyridine 
• 584-14-5 1-amino-1,2,3-triazole 
• 13518-80-4 2-trimethylsilyl-2H-1,2,3-triazole 
• 63778-00-7 2-phenethyl-2H-[1,2,3]triazole 
• 63777-90-2 2-phenylethyl-1H-1,2,3-triazole 
• 85862-90-4 1-(4-(1H-1,2,3-triazol-1-yl)phenyl)ethan-1-one 
• 420-04-2 CYANAMID 
• 24153-51-3 diazomethane 
• 151-51-9 carbodiimide 
• 18922-72-0 2-(4-nitrophenyl)-2H-1,2,3-triazole 
• 1001401-62-2 2-(2H-1,2,3-triazol-2-yl)benzoic acid 

Relevant articles and documents

Process for the manufacture of functional PFPE derivative

A process for the manufacture of a functional (per)fluoropolyether derivative comprising at least one triazole group, such process comprising: (1) reacting a (per)fluoropolyether hydroxyl derivative having at least one hydroxyl group [derivative (PFPE-OH)] with an activating agent, to yield an activated (per)fluoropolyether hydroxyl derivative comprising at least one activated hydroxyl group [derivative (a-PFPE-OH)]; (2) reacting said activated (per)fluoropolyether hydroxyl derivative [derivative (a-PFPE-OH)] with at least one azide salt to yield a functional (per)fluoropolyether derivative comprising at least one azido group [derivative (PFPE-N3)]; and (3) reacting said functional (per)fluoropolyether derivative comprising at least one azido group [derivative (PFPE-N3)] with a hydrocarbon compound having a terminal alkyne group to yield a functional (per)fluoropolyether derivative comprising at least one triazole group [derivative (PFPE-azole)].

Heteroaryl-phenyl substituted factor Xa inhibitors

The present application describes heteroaryl-phenyl substituted compounds and derivatives thereof, or pharmaceutically acceptable salt or prodrug forms thereof, which are useful as inhibitors of factor Xa.

Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa

The present application describes inhibitors of factor Xa of formula I: or pharmaceutically acceptable salt forms thereof, wherein W, W1, W2, and W3may be N or C and J, Ja, and Jbcombine to form a substituted carbocycle or heterocycle.