305371-16-8 Usage
Description
[6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER is a chemical compound characterized by its molecular formula C15H18FN3O4. It is a Tert-butyl ester derivative of [6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID, known for its potential role as an intermediate in the synthesis of pharmaceuticals and agrochemicals. [6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER holds promise in the field of medicinal chemistry and drug development due to its ability to serve as a building block for creating novel compounds with biological activity. It is crucial to review safety and handling information for this chemical, as it may possess hazardous properties and should be handled with caution in a laboratory setting.
Uses
Used in Pharmaceutical Industry:
[6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER is used as an intermediate compound for the synthesis of various pharmaceuticals. Its role in creating novel compounds with biological activity makes it a valuable asset in the development of new drugs and therapies.
Used in Agrochemical Industry:
In the agrochemical industry, [6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER is utilized as an intermediate in the synthesis of agrochemicals. Its potential to contribute to the development of new compounds with biological activity can lead to the creation of innovative products for agricultural applications, such as pesticides and fertilizers.
Used in Medicinal Chemistry Research:
[6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER is employed as a building block in medicinal chemistry research. Its ability to form novel compounds with biological activity makes it a valuable tool for scientists working on the design and synthesis of new drugs and therapeutic agents.
Used in Drug Development:
[6-FLUORO-4-(3-NITRILOPROPIONYL)PYRIDIN-3-YL]CARBAMIC ACID TERT-BUTYL ESTER is used as a key component in drug development, where its potential to create new biologically active compounds can contribute to the discovery of innovative treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 305371-16-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,3,7 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 305371-16:
(8*3)+(7*0)+(6*5)+(5*3)+(4*7)+(3*1)+(2*1)+(1*6)=108
108 % 10 = 8
So 305371-16-8 is a valid CAS Registry Number.
305371-16-8Relevant articles and documents
Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles
Wissner, Allan,Hamann, Philip R.,Nilakantan, Ramaswamy,Greenberger, Lee M.,Ye, Fei,Rapuano, Timothy A.,Loganzo, Frank
, p. 1411 - 1416 (2007/10/03)
The syntheses and EGFR kinase inhibitory activity of a series of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles are described. Both reversible and irreversible binding inhibitors were prepared. These series were compared with each other and with the corresponding 4-anilinoquinoline-3-carbonitriles. Compounds having a 1,7-naphthyridine core structure can retain high potency while those with a 1,8-naphthyridine core are significantly less active. These results are consistent with molecular modeling observations.
SUBSTITUTED 3-CYANO-[1.7], [1.5] AND [1.8] NAPHTHYRIDINE INHIBITORS OF TYROSINE KINASES
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Page column 65, (2010/02/05)
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