30611-21-3

Basic information

• Product Name: 4-PENTANOYL-BENZOIC ACID METHYL ESTER
• Synonyms: 4-PENTANOYL-BENZOIC ACID METHYL ESTER;4-(1-oxopentyl)benzoic acid Methyl ester;Methyl 4-pentanoylbenzoate
• CAS NO: 30611-21-3
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.26434
• Mol File: 30611-21-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 339.1±25.0 °C(Predicted)
• Appearance: /
• Density: 1.057±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-PENTANOYL-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PENTANOYL-BENZOIC ACID METHYL ESTER(30611-21-3)
• EPA Substance Registry System: 4-PENTANOYL-BENZOIC ACID METHYL ESTER(30611-21-3)

Safety Data

• Hazardous Substances Data: 30611-21-3(Hazardous Substances Data)

Usage

General Description

4-Pentanoyl-benzoic acid methyl ester, also known as ethyl 4-pentanoylbenzoate, is a chemical compound with the molecular formula C14H16O3. It is commonly used in the synthesis of pharmaceuticals and organic compounds due to its unique structural properties. This ester is an important intermediate in organic chemistry and can be used as a building block for the production of various pharmaceutical and industrial compounds. Its chemical structure gives it the ability to participate in a wide range of chemical reactions, making it a versatile and valuable compound in the field of organic synthesis.

Upstream product

• 79784-62-6 p-valerylbenzoic acid 
• 74-88-4 methyl iodide 
• 66534-32-5 α,α-diisopropyl-β-methylhomoallylic alcohol 
• 1571-08-0 methyl 4-formylbenzoate 
• 462-06-6 fluorobenzene 
• 30611-20-2 1-(4-cyanophenyl)-1-pentanone 
• 709-24-0 1-(4-fluorophenyl)-1-pentanone 
• 638-29-9 n-valeryl chloride 
• 108-86-1 bromobenzene 
• 7295-44-5 4'-bromovalerophenone 
• 7377-26-6 4-Methoxycarbonylbenzoyl chloride 
• 109-72-8 n-butyllithium 

Downstream Products

• 3609-53-8 methyl 4-acetylbenzoate 
• 30768-94-6 4-(2-bromopentanoyl)benzoic acid methyl ester 
• 30611-26-8 1-(4-hydroxymethylphenyl)pentan-1-one 
• 30611-27-9 2-bromo-1-(4-hydroxymethylphenyl)pentan-1-one 

Relevant articles and documents

Design, synthesis, and effects of novel phenylpyrimidines as glucagon receptor antagonists

The hormone glucagon increases blood glucose levels through increasing hepatic glucose output. In diabetic patients, dysregulation of glucagon secretion contributes to hyperglycemia. Thus, the inhibition of glucagon receptor is one target for the treatment of hyperglycemia in type 2 diabetes. Here we designed and synthesized a series of small molecules based on phenylpyrimidine. Of these, the compound (R)-7a most significantly decreased the glucagon-induced cAMP production and glucagon-induced glucose production during in vitro and in vivo assays. In addition, (R)-7a showed good efficacy in glucagon challenge tests and lowered blood glucose levels in diabetic db/db mice. Our results suggest that the compound (R)-7a could be a potential glucose-lowering agent for treating type 2 diabetes.

Synthesis of Functionalized Ketones from Acid Chlorides and Organolithiums by Extremely Fast Micromixing

Synthesis of ketones containing various functional groups from acid chlorides bearing electrophilic functional groups and functionalized organolithiums was achieved using a flow microreactor system. Extremely fast mixing is important for high chemoselectivity.

Rhodium-catalyzed allyl transfer from homoallyl alcohols to aldehydes via retro-allylation followed by isomerization into ketones

Retro-allylation of homoallyl alcohol by rhodium catalysis occurs to generate allylrhodium species. This allylrhodium reacts with aldehydes to give the corresponding secondary alcohols in situ. Isomerization of these alcohols proceeds in the same pots to furnish the corresponding saturated ketones in good yields.