30879-49-3

Basic information

• Product Name: 1-(5-hydroxy-2-nitrophenyl)ethanone
• Synonyms: 1-(5-hydroxy-2-nitrophenyl)ethanone;2-Nitro-5-hydroxyacetophenone;5'-Hydroxy-2'-nitroacetophenone;MFCD12827423
• CAS NO: 30879-49-3
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.146
• Mol File: 30879-49-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 146-147 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 391.2 °C at 760 mmHg
• Flash Point: 178.1 °C
• Appearance: /
• Density: 1.380
• Vapor Pressure: 1.12E-06mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 6.20±0.10(Predicted)
• CAS DataBase Reference: 1-(5-hydroxy-2-nitrophenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-hydroxy-2-nitrophenyl)ethanone(30879-49-3)
• EPA Substance Registry System: 1-(5-hydroxy-2-nitrophenyl)ethanone(30879-49-3)

Safety Data

• Hazardous Substances Data: 30879-49-3(Hazardous Substances Data)

Usage

Preparation

Preparation by nitration of 3-hydroxyacetophenone,with nitric acid (d = 1.4) in acetic acid, at 70° (31%), (15%)with cupric nitrate in acetic acid–acetic anhydride mixture, between 12° and 15° (20%).

InChI:InChI=1/C8H7NO4/c1-5(10)7-4-6(11)2-3-8(7)9(12)13/h2-4,11H,1H3

Upstream product

• 121-71-1 3-Hydroxyacetophenone 
• 1392043-83-2 bis(3-acetylphenyl) oxalate 

Downstream Products

• 42887-67-2 1-(5-methoxy-2-nitrophenyl)ethanone 
• 107916-74-5 6,6'-Dinitro-3,3'-dihydroxy-chalkon 
• 107916-68-7 4,6'-Dinitro-3,3'-dihydroxy-chalkon 
• 30954-71-3 2′-amino-5′-hydroxyacetophenone 
• 418759-59-8 5-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2-nitroacetophenone 
• 442853-29-4 20α-(3-acetyl-4-nitrophenoxymethyl)-3β-methoxy-5-pregnen 
• 708254-64-2 1-[2-nitro-5-(2-piperidin-1-yl-ethoxy)-phenyl]-ethanone 
• 708254-66-4 1-[2-amino-5-(2-piperidin-1-yl-ethoxy)-phenyl]-ethanone 
• 418759-61-2 1-[5-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2-nitrophenyl]ethanol 
• 418759-66-7 1-[5-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2-nitrophenyl] ethoxycarbonyl glycine methyl ester 
• 418759-62-3 1-[5-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2-nitrophenyl]ethyl 4-nitrophenyl carbonate 
• 418759-54-3 1-[5-O-(β-D-glucopyranosyl)-2-nitrophenyl]ethoxycarbonyl L-leucyl-L-leucine methyl ester 
• 418759-64-5 1-[5-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2-nitrophenyl]ethoxycarbonyl L-leucyl-L-leucine methyl ester 
• 23042-77-5 1-(2-amino-5-methoxy-phenyl)-ethanone 

Relevant articles and documents

Design, synthesis and evaluation of 1,3,6-trisubstituted-4-oxo-1,4-dihydroquinoline-2-carboxylic acid derivatives as ETA receptor selective antagonists using FRET assay

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