309735-34-0

Basic information

• Product Name: 2-Benzylthio-4-nitrobenzamide
• Synonyms: 2-Benzylthio-4-nitrobenzamide
• CAS NO: 309735-34-0
• Molecular Weight: 288.327
• Mol File: 309735-34-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Benzylthio-4-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzylthio-4-nitrobenzamide(309735-34-0)
• EPA Substance Registry System: 2-Benzylthio-4-nitrobenzamide(309735-34-0)

Safety Data

• Hazardous Substances Data: 309735-34-0(Hazardous Substances Data)

Upstream product

• 610-30-0 2,4-dinitrobenzoic acid 
• 20195-22-6 2,4-dinitrobenzoyl chloride 
• 13296-87-2 2,4-dinitrobenzamide 
• 100-53-8 phenylmethanethiol 

Downstream Products

• 335434-38-3 4-nitro-2-phenylmethanesulfonyl-benzamide 
• 22952-24-5 6-nitrosaccharin 
• 4337-51-3 6-Nitro-1,2-benzisothiazol-3-one 
• 335434-42-9 (4-nitro-2-phenylmethanesulfonyl-phenyl)-carbamic acid methyl ester 

Relevant articles and documents

Synthesis of 2,3-dihydrobenzothiazol-1,1-dioxide and 2,3-dihydro-1,4-benzothiazin-3-one nitroderivatives from 2,4-di- and 2,4,6-trinitrobenzamides

Synthetic methods for the conversion of readily available 2,4-di- and 2,4,6-trinitrobenzamides to the previously unknown 2,3-dihydrobenzothiazol-1,1-dioxide, 2,3-dihydro- 1,4-benzothiazin-3-one, and 2,3-dihydro-1,4-benzothiazin-3-one-1,1-dioxide nitroderivatives have been developed. The methods involve selective nucleophilic substitution of an ortho-nitrogroup in polynitrobenzamides by benzylthio or methoxycarbonylmethylthio group followed by oxidation of sulfur atom with hydrogen peroxide and transformation of the amido group to the methoxycarbonylamino group by reaction with diacetoxyiodobenzene in methanol under non-basic conditions. Cyclization of the resulting compounds under the action of diacetoxyiodobenzene or sodium methoxide leads to the 2,3-dihydrobenzothiazole and 2,3-dihydro-1,4-benzothiazin-3one derivatives, respectively.