314256-39-8Relevant articles and documents
6-MODIFIED BICYCLIC NUCLEIC ACID ANALOGS
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Page/Page column 14-15, (2010/11/28)
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.