3194-17-0

Basic information

• Product Name: 1-(2-FURYL)PENTAN-1-ONE
• Synonyms: 1-(2-FURYL)PENTAN-1-ONE;2-PENTANOYLFURAN;FEMA 4192;1-(2-Furyl)pentan-1-one (2-Pentanoylfuran );1-Pentanone, 1-(2-furanyl)-;1-(2-Furyl)pentan-1-one 97%;1-(2-FURYL)PENTAN-1-ONE 2-PENTANOYLFURAN;2-Valerylfuran, 97%
• CAS NO: 3194-17-0
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19
• Mol File: 3194-17-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 224.8 °C at 760 mmHg
• Flash Point: 97 °C
• Appearance: /
• Density: 0.992 g/cm³
• Vapor Pressure: 0.214mmHg at 25°C
• Refractive Index: 1.4920
• CAS DataBase Reference: 1-(2-FURYL)PENTAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-FURYL)PENTAN-1-ONE(3194-17-0)
• EPA Substance Registry System: 1-(2-FURYL)PENTAN-1-ONE(3194-17-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 36/37
• Hazardous Substances Data: 3194-17-0(Hazardous Substances Data)

Usage

Description

1-(2-FURYL)PENTAN-1-ONE is a colorless liquid with a sweet caramel aroma. It has a medium strength odor and is recommended to be smelled in a 10% solution or less.

Uses

Used in Flavor Industry:
1-(2-FURYL)PENTAN-1-ONE is used as a flavoring agent for its sweet caramel aroma, enhancing the taste and aroma of various food and beverage products.
Used in Fragrance Industry:
1-(2-FURYL)PENTAN-1-ONE is used as a fragrance ingredient for its medium strength odor, contributing to the creation of various scent profiles in perfumes, cosmetics, and other fragranced products.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 7179, 1985 DOI: 10.1021/ja00310a073Tetrahedron Letters, 36, p. 1287, 1995 DOI: 10.1016/0040-4039(95)00057-J

InChI:InChI=1/C9H12O2/c1-2-4-8(10)7-9-5-3-6-11-9/h3,5-6H,2,4,7H2,1H3

Upstream product

• 110-00-9 furan 
• 2082-59-9 pentanoic anhydride 
• 638-29-9 n-valeryl chloride 
• 617-90-3 2-furancarbonitrile 
• 693-03-8 n-butyl magnesium bromide 
• 98-01-1 furfural 
• 109-72-8 n-butyllithium 
• 527-69-5 2-furancarbonyl chloride 
• 62485-87-4 butyl-iodo-manganese 
• 30478-77-4 1-(furan-2-yl)pentan-1-ol 
• 33581-39-4 Furan-2-carbaldehyde O-methyl-oxime 
• 4885-02-3 Dichloromethyl methyl ether 
• 109529-23-9 (n-butyl)(2-furyl)(isopropoxy)borane 
• 97037-63-3 C₈H₈O₅ 

Downstream Products

• 99062-45-0 1-(furan-2-yl)pentan-1-amine 
• 360-34-9 1,1,1-trifluoro-2-hexanone 
• 614-99-3 Ethyl 2-furoate 

Relevant articles and documents

Acid-catalyzed oxidation of furan derivatives by t-butyl hydroperoxide

The unusual reactivity of t-butyl hydroperoxide under acid-catalysis allows the easy conversion of furan derivatives into 3(6H)-pyranones.

A simple synthesis of ketone from carboxylic acid using tosyl chloride as an activator

An effective process for the conversion of carboxylic acid to ketone has been discovered. In this process, carboxylic acid has been activated using p-toluene sulphonyl group. Under the optimized condition, aromatic, aliphatic heteroaromatic carboxylic acids have been proved to be good substrates for this methodology. The byproduct of this reaction can be removed very easily during work up process. Also, one equivalent of organometallic reagent is sufficient to complete this transformation.

An effective one-pot conversion of acid chlorides to aldehydes and ketones

Aldehydes and ketones were synthesized from their respective acid chlorides via a one-pot protocol. Morpholine amide intermediates that were readily prepared by the aminolysis of various acid chlorides with diisobutyl(morpholino) aluminum smoothly reacted with the reducing agent LDBMA and the organolithium reagents under mild reaction conditions (0 C), giving almost excellent product yields of up to 95%.