325457-63-4 Usage
Description
[1,1'-Biphenyl]-3-carbonitrile, 3'-(broMoMethyl)is a chemical compound with the molecular formula C15H10BrN, belonging to the aromatic hydrocarbons group. It features a carbonitrile functional group, which is a carbon atom triple-bonded to a nitrogen atom, and a bromomethyl group, where a bromine atom is bonded to a methyl group. [1,1'-Biphenyl]-3-carbonitrile, 3'-(broMoMethyl)may have potential applications in organic synthesis, pharmaceuticals, and materials science, with its specific uses depending on its unique chemical and physical properties.
Uses
Used in Organic Synthesis:
[1,1'-Biphenyl]-3-carbonitrile, 3'-(broMoMethyl)is used as an intermediate in the synthesis of various organic compounds due to its unique functional groups, which can be further modified or reacted to produce a range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [1,1'-Biphenyl]-3-carbonitrile, 3'-(broMoMethyl)is used as a building block for the development of new drugs. Its specific functional groups can be exploited to create molecules with desired biological activities, potentially leading to the discovery of novel therapeutic agents.
Used in Materials Science:
[1,1'-Biphenyl]-3-carbonitrile, 3'-(broMoMethyl)may also find applications in materials science, where its unique chemical structure could be utilized to develop new materials with specific properties, such as improved conductivity, strength, or stability.
Check Digit Verification of cas no
The CAS Registry Mumber 325457-63-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,5,4,5 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 325457-63:
(8*3)+(7*2)+(6*5)+(5*4)+(4*5)+(3*7)+(2*6)+(1*3)=144
144 % 10 = 4
So 325457-63-4 is a valid CAS Registry Number.
325457-63-4Relevant articles and documents
Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors
Huang, Wenrong,Zhang, Penglie,Zuckett, Jingmei F.,Wang, Lingyan,Woolfrey, John,Song, Yonghong,Jia, Zhaozhong J.,Clizbe, Lane A.,Su, Ting,Tran, Katherine,Huang, Brian,Wong, Paul,Sinha, Uma,Park, Gary,Reed, Andrea,Malinowski, John,Hollenbach, Stanley J.,Scarborough, Robert M.,Zhu, Bing-Yan
, p. 561 - 566 (2007/10/03)
A series of benzoxazinone derivatives was designed and synthesized as factor Xa inhibitors. We demonstrated that the naphthyl moiety in the aniline-based compounds 1 and 2 can be replaced with benzene-fused heterobicycles and biaryls to give factor Xa inh
Benzimidazole-Based fXa inhibitors with improved thrombin and trypsin selectivity
Shaw, Kenneth J.,Guilford, William J.,Griedel, Brian D.,Sakata, Steve,Trinh, Lan,Wu, Shung,Xu, Wei,Zhao, Zuchun,Morrissey, Michael M.
, p. 1311 - 1314 (2007/10/03)
Optimization of the benzimidazole-based fXa inhibitors for selectivity versus thrombin and trypsin was achieved by substitution on the benzimidazole ring and replacement of the naphthylamidine group. Substitution of a nitro group at the 4-position on the benzimidazole improves both potency against fXa and selectivity versus thrombin. Alternatively, replacement of the naphthylamidine with either a biphenylamidine or propenylbenzamidine not only improves fXa potency and selectivity versus thrombin, but selectivity versus trypsin as well.
