364614-53-9

Basic information

• Product Name: ((3'-carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-sulfamoyl)-acetic acid ethyl ester
• CAS NO: 364614-53-9
• Molecular Weight: 591.731
• Mol File: 364614-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((3'-carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-sulfamoyl)-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((3'-carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-sulfamoyl)-acetic acid ethyl ester(364614-53-9)
• EPA Substance Registry System: ((3'-carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-sulfamoyl)-acetic acid ethyl ester(364614-53-9)

Safety Data

• Hazardous Substances Data: 364614-53-9(Hazardous Substances Data)

Upstream product

• 2208-07-3 ethyl acetimidate hydrochloride 
• 544694-81-7 4-{4-[(3'-carbamimidoyl-biphenyl-3-ylmethyl)-ethoxycarbonylmethanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester 
• 400748-29-0 3'-formyl-[1,1'-biphenyl]-3-carbonitrile 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 
• 138227-63-1 tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate 
• 325457-63-4 3-(3-cyanophenyl)-1-(bromomethyl)benzene 
• 247183-18-2 3-(3-cyanophenyl)-1-methylbenzene 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 150255-96-2 (3‐cyanophenyl)boronic acid 
• 350-46-9 4-Fluoronitrobenzene 
• 591-17-3 meta-bromotoluene 

Relevant articles and documents

Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors

A series of benzoxazinone derivatives was designed and synthesized as factor Xa inhibitors. We demonstrated that the naphthyl moiety in the aniline-based compounds 1 and 2 can be replaced with benzene-fused heterobicycles and biaryls to give factor Xa inh