325855-74-1 Usage
Description
5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide is a chemical compound that is identified as an impurity of Etoricoxib, a nonsteroidal anti-inflammatory drug (NSAID) used for treating various types of pain and inflammation.
Uses
Used in Pharmaceutical Industry:
5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide is used as an impurity in the manufacturing process of Etoricoxib (E934100). Its presence is monitored and controlled to ensure the quality and safety of the final pharmaceutical product.
Check Digit Verification of cas no
The CAS Registry Mumber 325855-74-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,5,8,5 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 325855-74:
(8*3)+(7*2)+(6*5)+(5*8)+(4*5)+(3*5)+(2*7)+(1*4)=161
161 % 10 = 1
So 325855-74-1 is a valid CAS Registry Number.
325855-74-1Relevant articles and documents
A general [3 + 2 + 1] annulation strategy for the preparation of pyridine N-oxides
Davies, Ian W.,Marcoux, Jean-Francois,Reider, Paul J.
, p. 209 - 211 (2001)
equation presented Stabilized ketone, aldehyde, and ester enolates react with vinamidinium hexafluorophosphate salts and hydroxylamine hydrochloride to give access to the corresponding pyridine N-oxides. The annulation reactions proceed in good to excelle