327-52-6 Usage
Description
1-Bromo-2,4,5-trifluorobenzene is an organic compound characterized by the presence of a bromine atom and three fluorine atoms attached to a benzene ring. It is a versatile intermediate in the synthesis of various chemical compounds and has applications in different industries.
Uses
Used in Pharmaceutical Industry:
1-Bromo-2,4,5-trifluorobenzene is used as an intermediate for the synthesis of quinolone antibacterial agents, which are important in the development of new drugs to combat bacterial infections.
Used in Liquid Crystal Industry:
1-Bromo-2,4,5-trifluorobenzene serves as an intermediate in the production of liquid crystals, which are widely used in display technologies such as televisions, computer monitors, and smartphones.
Used in Chemical Synthesis:
1-Bromo-2,4,5-trifluorobenzene is employed in the synthesis of various 3-substituted-2,4,5-trifluorobenzoic acids, including 3-ethenyl, 3-ethynyl, 3-aryl, and 3-cyclopropyl derivatives. These compounds have potential applications in various fields, such as pharmaceuticals, materials science, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 327-52-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 327-52:
(5*3)+(4*2)+(3*7)+(2*5)+(1*2)=56
56 % 10 = 6
So 327-52-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3N2/c9-8(10,11)6-3-5(4-12)1-2-7(6)13/h1-3H,13H2
327-52-6Relevant articles and documents
PROCESS FOR THE PREPARATION OF 1-BROMO-2,4,5-TRIFLUOROBENZENE
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Page/Page column 12-13; 17-18, (2021/09/17)
The present invention relates to a process for the preparation of l-bromo-2,4,5-trifluorobenzene from 2,4,5-trifhioroaniline or sulfate salt thereof. The present invention also relates to a process for the preparation of 1,2,4-trifluorobenzene from 2,4,5-trifluoroaniline and then converting into 1-bromo-2,4,5 -trifluorobenzene.
Efficient preparation method of 2, 4, 5-trifluorophenylacetic acid
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, (2018/03/26)
The invention discloses an efficient preparation method of 2, 4, 5-trifluorophenylacetic acid and belongs to the technical field of synthesis of a pharmaceutical intermediate. The preparation method comprises synthesis of 2, 3, 5-trifluoroaniline, synthesis of 1, 2, 4-trifluorobenzene, synthesis of trifluorobromobenzene and synthesis of a desired product 2, 4, 5-trifluorophenylacetic acid. The preparation method is simple and easy to operate, utilizes cheap and easily available raw materials and has high reaction efficiency and good repeatability.
PROCESS FOR THE PREPARATION OF ORGANIC BROMIDES
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Paragraph 00139, (2017/07/28)
The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.