330636-42-5

Basic information

• Product Name: 1-[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-ethanone
• Synonyms: 1-[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-ethanone
• CAS NO: 330636-42-5
• Molecular Weight: 267.26
• Mol File: 330636-42-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-ethanone(330636-42-5)
• EPA Substance Registry System: 1-[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-ethanone(330636-42-5)

Safety Data

• Hazardous Substances Data: 330636-42-5(Hazardous Substances Data)

Upstream product

• 13889-98-0 N-acetylpiperidine 
• 369-34-6 3,4-difluoronitrobenzene 
• 108-24-7 acetic anhydride 
• 154590-33-7 1-(2-fluoro-4-nitrophenyl)piperazine 
• 75-36-5 acetyl chloride 

Downstream Products

• 864146-95-2 1-[4-(4-amino-2-fluorophenyl)piperazin-1-yl]ethanone 

Relevant articles and documents

Design, synthesis and SAR study of 2-aminopyrimidines with diverse Michael addition acceptors for chemically tuning the potency against EGFRL858R/T790M

The covalent binding nature of irreversible kinase inhibitors potentially increases the severity of “off-target” toxicity. Based on our continual strategy of chemically tuning the Michael addition acceptors, herein, we further explore the relationship amo

N-(3,4-disubstituted phenyl) salicylamide derivatives

A compound represented by the following formula (I) or a salt thereof: wherein R1, R2, R3 and R4 represent hydrogen atom, a halogen atom, cyano group, nitro group, a C1-4 alkyl group, a halogenated C

IMIDAZOLO-5-YL-2-ANILINOPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION

Compounds of the formula (I), wherein variable groups are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti cell proliferation) effect in a warm blooded animal, such as man.