864146-95-2 Usage
General Description
4-(4-Acetyl-piperazin-1-yl)-2-fluoroaniline, also known as FIASP, is a chemical compound that belongs to the class of organic compounds known as aniline and substituted derivatives. It is commonly used as a building block in the synthesis of various pharmaceutical drugs and agrochemicals. FIASP is a potential inhibitor of the enzyme caspase-3, which plays a key role in apoptosis. 4-(4-Acetyl-piperazin-1-yl)-2-fluoroaniline also has potential antineoplastic and anticonvulsant properties. FIASP is a white to beige powder that is soluble in dilute acids and alkalis, and has a molecular formula of C12H16FN3O. It is important to handle FIASP with caution due to its potential health hazards and environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 864146-95-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,1,4 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 864146-95:
(8*8)+(7*6)+(6*4)+(5*1)+(4*4)+(3*6)+(2*9)+(1*5)=192
192 % 10 = 2
So 864146-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H16FN3O/c1-9(17)15-4-6-16(7-5-15)10-2-3-12(14)11(13)8-10/h2-3,8H,4-7,14H2,1H3
864146-95-2Relevant articles and documents
Design, synthesis and SAR study of 2-aminopyrimidines with diverse Michael addition acceptors for chemically tuning the potency against EGFRL858R/T790M
Chen, Wenteng,Liu, Shuangrong,Liu, Xingyu,Pan, Youlu,Shao, Jiaan
, (2020/08/10)
The covalent binding nature of irreversible kinase inhibitors potentially increases the severity of “off-target” toxicity. Based on our continual strategy of chemically tuning the Michael addition acceptors, herein, we further explore the relationship amo
N-(3,4-disubstituted phenyl) salicylamide derivatives
-
Page/Page column 44, (2008/12/07)
A compound represented by the following formula (I) or a salt thereof: wherein R1, R2, R3 and R4 represent hydrogen atom, a halogen atom, cyano group, nitro group, a C1-4 alkyl group, a halogenated C
