333382-86-8

Basic information

• Product Name: 2-(2-(2-(4-bromophenoxy)ethoxy)ethoxy)ethan-1-ol
• Synonyms: 2-(2-(2-(4-bromophenoxy)ethoxy)ethoxy)ethan-1-ol
• CAS NO: 333382-86-8
• Molecular Weight: 305.169
• Mol File: 333382-86-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(2-(2-(4-bromophenoxy)ethoxy)ethoxy)ethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(2-(4-bromophenoxy)ethoxy)ethoxy)ethan-1-ol(333382-86-8)
• EPA Substance Registry System: 2-(2-(2-(4-bromophenoxy)ethoxy)ethoxy)ethan-1-ol(333382-86-8)

Safety Data

• Hazardous Substances Data: 333382-86-8(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 77544-68-4 8-tosyloxy-3,6-dioxaoctanol 
• 19249-03-7 triethylene glycol di-(p-toluenesulfonate) 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 123824-56-6 1-bromo-6-phenyl-3,6-dioxahexane 
• 7204-16-2 2-(2-(2-phenoxyethoxy)ethoxy)ethan-1-ol 
• 104-68-7 2-(2-phenoxyethoxy)ethanol 

Downstream Products

• 333382-92-6 2,6-bis-(2-{2-[2-(4-vinyl-phenoxy)-ethoxy]-ethoxy}-ethoxymethyl)-pyridine 
• 333383-18-9 oligo(ethylene glycol)mono(p-vinylphenyl)ether 

Relevant articles and documents

Solvent-assisted organized structures based on amphiphilic anion-responsive π-conjugated systems

synthesis of amphiphilic π-conjugated acyclic oligopyrroles and the formation of solvent-assisted aggregates are reported. We have prepared various types of BF2 complexes of 1,3-dipyrrolylpropane-1,3-diones bearing aryl rings substituted with h

Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers

Taking advantage of click chemistry, a library of N-arylpiperazinylmethyl triazoles bearing fluoro substituted appendages was synthesized and the target compounds were investigated for dopamine and serotonin receptor binding. With the aim to bias their hydrophilicity and to optimize their D4 receptor affinity and selectivity, a concise series of triazoles containing fluoroalkyl, fluoroalkoxy, fluoroalkoxyphenyl, and deoxyfluoroglucosyl substituents was studied. The D4 receptor affinity and selectivity could be tuned by altering the chemical moiety attached to the triazole unit. Among the test compounds, the fluoroethoxyphenyl derivative 15b showed weak partial agonism at D4 and a K i value of 14 nM, while its fluoropropoxyphenyl homologue 16a turned out to act as a neutral D4 antagonist (Ki = 5.1 nM). Both, 15b and 16a revealed an excellent balance between D4 receptor affinity and subtype selectivity, providing lead candidates for the development of 18F-labeled radioligands for D4 receptor imaging studies by positron emission tomography (PET).

Synthesis of pyridinocrownophanes exhibiting high Ag+-affinity

Crownophanes possessing a pyridine moiety were prepared by means of intramolecular [2 + 2] photocycloaddition of the styrene derivatives. The crown compounds having six to ten ethereal oxygens selectively extracted Ag+ with high efficiency in the liquid-liquid extraction. The high extractability and efficiency were maintained even at low pH region of the extraction system. From ESI-MS analysis, it was found that the crownophanes formed some kinds of complexes having 1:1 and 2:1 stoichiometry (host/guest) with Ag+ and Pb2+ in MeCN-H2O homogeneous system.