33693-67-3 Usage
Description
ALPHA-BROMO-ALPHA-METHYL-GAMMA-BUTYROLACTONE, a lactone derivative, is a chemical compound that has been found to be hydrolyzed by paraoxonase/arylesterase (PON1), a purified rabbit serum enzyme. This characteristic makes it an interesting compound for further research and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
ALPHA-BROMO-ALPHA-METHYL-GAMMA-BUTYROLACTONE is used as a research compound for understanding the hydrolysis process by PON1 enzyme. Its interaction with the enzyme can provide insights into the development of new drugs or therapies that target this enzyme, potentially leading to treatments for various diseases.
Used in Chemical Research:
ALPHA-BROMO-ALPHA-METHYL-GAMMA-BUTYROLACTONE serves as a valuable compound in chemical research, particularly in the study of lactone derivatives and their interactions with enzymes. This knowledge can contribute to the development of new chemical compounds with specific applications in various industries.
Used in Enzyme Studies:
As a substrate for the PON1 enzyme, ALPHA-BROMO-ALPHA-METHYL-GAMMA-BUTYROLACTONE is used in enzyme studies to investigate the enzyme's activity, specificity, and potential roles in biological processes. Understanding the enzyme's function can lead to the discovery of new therapeutic targets and the development of novel drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 33693-67-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,6,9 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 33693-67:
(7*3)+(6*3)+(5*6)+(4*9)+(3*3)+(2*6)+(1*7)=133
133 % 10 = 3
So 33693-67-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H7BrO2/c1-5(6)2-3-8-4(5)7/h2-3H2,1H3
33693-67-3Relevant articles and documents
Preparation of α-Hydroxy-γ-lactones and their Application in the Synthesis of α,β-Butenolides, α-Alkylidene-γ-lactones and Furans
Munoz, A. Heber,Tamariz, Joaquin,Jimenez, Rogelio,Mora, Gustavo Garcia de la
, p. 501 - 522 (2007/10/02)
A straightforward synthesis of α-hydroxy-γ-butyrolactones was carried out by condensation reaction of the lithium anion of ethoxyethyl-protected cyanohydrins with epoxides, followed by acidic treatment.Synthetic applications of these synthons in the preparation of interesting α,β-butenolides, α-alkylidene-γ-lactones and furans are described.