348640-19-7 Usage
General Description
3-Borono-5-methoxy-1H-indole-1-carboxylic acid 1-(1,1-dimethylethyl) ester is a chemical compound that is used in organic synthesis and medicinal chemistry. It is a boronic acid derivative of 5-methoxyindole carboxylic acid, and the tert-butyl ester group provides stability and protection to the compound. This chemical has been studied for its potential use in the development of new drugs, particularly in the treatment of cancer and inflammatory diseases. Its boron atom is known to interact with biological targets and has the potential to modulate biological processes, making it an interesting compound for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 348640-19-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,8,6,4 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 348640-19:
(8*3)+(7*4)+(6*8)+(5*6)+(4*4)+(3*0)+(2*1)+(1*9)=157
157 % 10 = 7
So 348640-19-7 is a valid CAS Registry Number.
348640-19-7Relevant articles and documents
Design of potent IGF1-R inhibitors related to bis-azaindoles
Nemecek, Conception,Metz, William A.,Wentzler, Sylvie,Ding, Fa-Xiang,Venot, Corinne,Souaille, Catherine,Dagallier, Anne,Maignan, Sebastien,Guilloteau, Jean-Pierre,Bernard, Francois,Henry, Alain,Grapinet, Sandrine,Lesuisse, Dominique
, p. 100 - 106 (2011/03/19)
From an azaindole lead, identified in high throughput screen, a series of potent bis-azaindole inhibitors of IGF1-R have been synthesized using rational drug design and SAR based on a in silico binding mode hypothesis. Although the resulting compounds produced the expected improved potency, the model was not validated by the co-crystallization experiments with IGF1-R.
