353290-51-4

Basic information

• Product Name: 1-(2-benzyloxy-ethyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid ethyl ester
• Synonyms: 1-(2-benzyloxy-ethyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid ethyl ester
• CAS NO: 353290-51-4
• Molecular Weight: 369.393
• Mol File: 353290-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-benzyloxy-ethyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-benzyloxy-ethyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid ethyl ester(353290-51-4)
• EPA Substance Registry System: 1-(2-benzyloxy-ethyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid ethyl ester(353290-51-4)

Safety Data

• Hazardous Substances Data: 353290-51-4(Hazardous Substances Data)

Upstream product

• 353290-44-5 2-Chloroethyl 6-fluoro-4-oxo-1,4-dihydro-2-quinolinecarboxylate 
• 353290-45-6 7-fluoro-3,4-dihydro-2-oxa-4a-aza-phenanthrene-1,9-dione 
• 19271-19-3 methyl 6-fluoro-1,4-dihydro-4-oxoquinoline-2-carboxylate 
• 100-39-0 benzyl bromide 
• 75-03-6 ethyl iodide 
• 353290-46-7 1-(2-benzyloxy-ethyl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid 

Relevant articles and documents

A convenient selective N-alkylation of 4-oxo-1,4-dihydro-2-quinoline carboxylic acid

The selective N-alkylation of 4-oxo-1,4-dihydro-2-quinoline carboxylic acid has been achieved from 1,2-dihydro[1,4]oxazino [4,3-a]quinoline-4,6-dione by the 2-morpholinone ring opening. In the same time, we have developed a new methodology to obtain the 1,2-dihydro[1,4]oxazino[4,3-a]quinoline-4,6-dione that involves an intramolecular cyclization of the 2-chloroethyl 6-fluoro-4-oxo-1,4-dihydro-2-quinoline carboxylate.