36404-88-3 Usage
Description
2-Chloro-3-pyridinecarboxaldehyde is an organic compound characterized by the presence of a chlorine atom at the 2nd position and a formyl group at the 3rd position on a pyridine ring. It is a versatile intermediate in organic synthesis and possesses valuable chemical properties that make it suitable for various applications.
Uses
Used in Pharmaceutical Industry:
2-Chloro-3-pyridinecarboxaldehyde is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those with potential therapeutic applications. Its unique structure allows for the development of new drugs with improved efficacy and selectivity.
Used in Organic Synthesis:
2-Chloro-3-pyridinecarboxaldehyde is used as a starting material for the preparation of 5-azaindoles through the Hemetsberger-Knittel reaction. This reaction involves the thermal decomposition of alkenyl azides, leading to the formation of 5-azaindole derivatives. These compounds have potential applications in various fields, including pharmaceuticals and materials science.
Used as Azaindazole Intermediate:
2-Chloro-3-pyridinecarboxaldehyde is utilized as an intermediate in the synthesis of azaindazole compounds. Azaindazoles are a class of heterocyclic compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science. The unique properties of azaindazoles make them valuable building blocks for the development of new molecules with specific functions and activities.
Check Digit Verification of cas no
The CAS Registry Mumber 36404-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,4,0 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 36404-88:
(7*3)+(6*6)+(5*4)+(4*0)+(3*4)+(2*8)+(1*8)=113
113 % 10 = 3
So 36404-88-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClNO/c7-6-5(4-9)2-1-3-8-6/h1-4H
36404-88-3Relevant articles and documents
Synthesis of a 1,8-napththyridin-5-one derivative via an intramolecular 1,3-dipolar cycloaddition reaction
Read,Ray
, p. 1595 - 1597 (1995)
Synthesis of a 1,8-naphthyridin-5-one derivative [(5,6,7,8-tetrahydro-(3-chloro-6-hydroxymethyl-8-methyl)-1,8-naphthyri din-5-one (9)] is described starting from 2-chloronicotinic acid using an intramolecular 1,3-dipolar cycloaddition reaction as the key step.
FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS
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Paragraph 0363, (2018/05/03)
Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, N-oxides, or solvates thereof, Also provided herein are pharmaceutical compositions comprising compounds of Formula (I) and methods of using compounds of Formula (I).
PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS
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Page/Page column 51, (2016/07/05)
Compounds of the general formula(I): (I) processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.
