37153-52-9

Basic information

• Product Name: BROMOCLENBUTEROL
• Synonyms: BROMOCLENBUTEROL
• CAS NO: 37153-52-9
• Molecular Formula: C12H18BrClN2O
• Molecular Weight: 321.64
• Mol File: 37153-52-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 430.3°Cat760mmHg
• Flash Point: 214°C
• Appearance: /
• Density: 1.424g/cm³
• Vapor Pressure: 3.61E-08mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: BROMOCLENBUTEROL(CAS DataBase Reference)
• NIST Chemistry Reference: BROMOCLENBUTEROL(37153-52-9)
• EPA Substance Registry System: BROMOCLENBUTEROL(37153-52-9)

Safety Data

• Hazardous Substances Data: 37153-52-9(Hazardous Substances Data)

Usage

Uses

Bromoclenbuterol is a β-agonist in human urine.

InChI:InChI=1/C12H18BrClN2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3

Upstream product

• 6953-83-9 1-(4-amino-3-chlorophenyl)ethan-1-one 
• 75-64-9 tert-butylamine 
• 60677-40-9 4-amino-3-bromo-5-chloroacetophenone 
• 99-92-3 p-aminobenzophenone 

Relevant articles and documents

Phenylethanolamine β receptor agonist synthetic method

The invention discloses a phenylethanolamine β receptor agonist synthetic method, comprises the following steps: S1: the 4 - amino acetophenone dissolved in an organic solvent, with the electrophilic reagent occurs on the benzene ring substituted halogenated reaction, generating [...] intermediate; [...] intermediates in organic solvent or in water, under the catalysis of the metal catalyst with the cyanide reagent undergo nucleophilic substitution reaction, generating phenyl ketone intermediate; S2: phenyl ketone intermediates in organic solvent, with the copper bromide generating carbonyl α bromo reaction to produce α - bromoacetophenone intermediates; S3: α - bromoacetophenone intermediates in organic solvent with tert-butyl amine or isopropylamine reaction intermediates acetophenone amines; S4: acetophenone amine intermediates in organic solvent, with the reduction hydrogenation reagent react to generate the phenylethanolamine β receptor agonists; synthetic method of this invention a simple and highly efficient and cheap and easy to obtain, atom utilization is high, the synthetic product chemical purity is greater than 99%, to meet the detection requirements of the food safety.