37728-89-5

Basic information

• Product Name: 1-(1,2-dibromoethyl)-3-methoxybenzene
• Synonyms: 1-(1,2-dibromoethyl)-3-methoxybenzene
• CAS NO: 37728-89-5
• Molecular Weight: 293.986
• Mol File: 37728-89-5.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1-(1,2-dibromoethyl)-3-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,2-dibromoethyl)-3-methoxybenzene(37728-89-5)
• EPA Substance Registry System: 1-(1,2-dibromoethyl)-3-methoxybenzene(37728-89-5)

Safety Data

• Hazardous Substances Data: 37728-89-5(Hazardous Substances Data)

Upstream product

• 626-20-0 3-methoxystyrene 
• 5020-41-7 2-(3-methoxyphenyl)-ethanol 

Downstream Products

• 1621387-10-7 2-((1-(3-methoxyphenyl)vinyl)oxy)isoindoline-1,3-dione 
• 1621387-25-4 C₉H₁₁BO₃ 
• 69151-19-5 1-(1-bromovinyl)-3-methoxybenzene 

Relevant articles and documents

Electrochemical Synthesis of O-Phthalimide Oximes from α-Azido Styrenes via Radical Sequence: Generation, Addition and Recombination of Imide-N-Oxyl and Iminyl Radicals with C?O/N?O Bonds Formation

Electrochemically induced radical-initiated reaction of vinyl azides with N-hydroxyphthalimide resulting O-phthalimide oximes with challenging for organic chemistry N?O-N fragment has been discovered. The developed approach introduces in synthesis electrochemically generated O-centered imide-N-oxyl radicals as the coupling components. Sequential formation of C?O and N?O bonds was achieved via generation and selective addition of imide-N-oxyl radicals, followed by recombination with iminyl radicals. A wide range of O-phthalimide oximes was obtained with the yields up to 84percent. (Figure presented.).

Rh(III)-Catalyzed C-H Activation-Initiated Directed Cyclopropanation of Allylic Alcohols

We have developed a Rh(III)-catalyzed diastereoselective [2+1] annulation onto allylic alcohols initiated by alkenyl C-H activation of N-enoxyphthalimides to furnish substituted cyclopropyl-ketones. Notably, the traceless oxyphthalimide handle serves three functions: directing C-H activation, oxidation of Rh(III), and, collectively with the allylic alcohol, in directing cyclopropanation to control diastereoselectivity. Allylic alcohols are shown to be highly reactive olefin coupling partners leading to a directed diastereoselective cyclopropanation reaction, providing products not accessible by other routes.

Rhodium(III)-Catalyzed Cyclopropanation of Unactivated Olefins Initiated by C-H Activation

We have developed a rhodium(III)-catalyzed cyclopropanation of unactivated olefins initiated by an alkenyl C-H activation. A variety of 1,1-disubstituted olefins undergo efficient cyclopropanation with a slight excess of alkene stoichiometry. A series of mechanistic interrogations implicate a metal carbene as an intermediate.