390360-63-1

Basic information

• Product Name: 10-(4-methoxy-phenyl)-19-nitro-9,12-dioxo-11-phenyl-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]heneicosa-1⁽¹⁹⁾,3,5,7⁽²¹⁾,16⁽²⁰⁾,17-hexaene-14-carboxylic acid ethyl ester
• CAS NO: 390360-63-1
• Molecular Weight: 609.635
• Mol File: 390360-63-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 10-(4-methoxy-phenyl)-19-nitro-9,12-dioxo-11-phenyl-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]heneicosa-1⁽¹⁹⁾,3,5,7⁽²¹⁾,16⁽²⁰⁾,17-hexaene-14-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 10-(4-methoxy-phenyl)-19-nitro-9,12-dioxo-11-phenyl-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]heneicosa-1⁽¹⁹⁾,3,5,7⁽²¹⁾,16⁽²⁰⁾,17-hexaene-14-carboxylic acid ethyl ester(390360-63-1)
• EPA Substance Registry System: 10-(4-methoxy-phenyl)-19-nitro-9,12-dioxo-11-phenyl-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]heneicosa-1⁽¹⁹⁾,3,5,7⁽²¹⁾,16⁽²⁰⁾,17-hexaene-14-carboxylic acid ethyl ester(390360-63-1)

Safety Data

• Hazardous Substances Data: 390360-63-1(Hazardous Substances Data)

Upstream product

• 389634-80-4 2-(4-fluoro-3-nitro-benzyl)-2-formylamino-malonic acid diethyl ester 
• 15017-52-4 4-(bromomethyl)-1-fluoro-2-nitrobenzene 
• 459-57-4 4-fluorobenzaldehyde 
• 42564-51-2 4-fluoro-3-nitrobenzaldehyde 
• 20274-69-5 (4-fluoro-3-nitrophenyl)methanol 
• 389634-81-5 3-(4-fluoro-3-nitro-phenyl)-2-formylamino-propionic acid ethyl ester 
• 389634-82-6 3-(4-fluoro-3-nitrophenyl)-2-isocyanopropionic acid ethyl ester 
• 104-94-9 4-methoxy-aniline 
• 100-52-7 benzaldehyde 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 627535-85-7 3-(4-Fluoro-3-nitro-phenyl)-2-{2-[[2-(3-hydroxy-phenyl)-acetyl]-(4-methoxy-phenyl)-amino]-2-phenyl-acetylamino}-propionic acid ethyl ester 

Downstream Products

• 389635-04-5 9,12-dioxo-2-oxa-10-(4'-methoxyphenyl)-11-phenyl-14-ethoxycarbonyl-18-amino-10,13-diazatricyclo[14.2.2.1^3,7]heneicosa-3,5,7⁽²¹⁾,16,18,19-hexaene 

Relevant articles and documents

Rapid and diverse route to natural product-like biaryl ether containing macrocycles

A two-step sequence involving an Ugi four-component reaction and an intramolecular nucleophilic aromatic substitution (SNAr) has been developed for the rapid access to biaryl-ether containing macrocycles. In the course of this study, we documented that ammonium chloride can promote the Ugi-4CR in non-polar aprotic solvent (toluene) without the interference of an alternative Passerini reaction. Solid phase synthesis of macrocycles by this two-step sequence was also developed using polymer (Wang resin) supported α-(4′-fluoro-3′-nitro)phenethyl isocyanoacetate as one of the inputs.