40145-10-6Relevant articles and documents
Thermal Cycloreversion of 2,2-Dimethyl-6-(ω-hydroxyalkyl)-4H-1,3-dioxin-4-ones: Mono-, Di-, and Trimeric Macrocyclic β-Keto Lactones by Intramolecular Trapping of (ω-Hydroxy)acylketenes
Chen, Chixu,Quinn, Erik K.,Olmstead, Marilyn M.,Kurth, Mark J.
, p. 5011 - 5014 (1993)
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Straightforward Synthesis of Fluorinated Enals via Photocatalytic α-Perfluoroalkenylation of Aldehydes
Wulkesch, Christian,Czekelius, Constantin
, p. 7425 - 7438 (2021/06/21)
(Per)fluorinated substances represent an important compound class with regard to drug design and material chemistry. We found a mild, operationally simple, and inexpensive photocatalytic perfluoroalkenylation reaction giving tetrasubstituted, highly electron-deficient enals straight from aldehydes. This one-step reaction tolerates various functional groups and can be applied to a wide range of substrates giving the products in yields of 52-84%.
Transition-Metal-Free Borylation of Alkyl Iodides via a Radical Mechanism
Liu, Qianyi,Hong, Junting,Sun, Beiqi,Bai, Guangcan,Li, Feng,Liu, Guoquan,Yang, Yang,Mo, Fanyang
supporting information, (2019/07/08)
We describe an operationally simple transition-metal-free borylation of alkyl iodides. This method uses commercially available diboron reagents as the boron source and exhibits excellent functional group compatibility. Furthermore, a diverse range of prim
Application of "click" chemistry in solid phase synthesis of alkyl halides
Das, Diparjun,Chanda, Tridib,Rokhum, Lalthazuala
, p. 775 - 783 (2016/01/20)
A convenient and highly selective microwave assisted procedure for the conversion of allylic, benzylic and aliphatic alcohols to their corresponding halides using polymer-bound triphenylphosphine and iodine is presented. In case of symmetrical diols, mono-iodination product is obtained in very high yield. Additionally, highly regioselective behavior is observed in our procedure. Simplicity in operation, no column chromatography required for the purification of the products, recyclability of the reagents used, short reaction times and good to excellent yields are the advantages of our protocol. Most functional groups remain unaffected under our reaction condition.