40165-88-6Relevant articles and documents
A fatty acid glycoside from a marine-derived fungus isolated from mangrove plant Scyphiphora hydrophyllacea
Zeng, Yan-Bo,Wang, Hui,Zuo, Wen-Jian,Zheng, Bo,Yang, Tao,Dai, Hao-Fu,Mei, Wen-Li
, p. 598 - 603 (2012)
To study the antimicrobial components from the endophytic fungus A1 of mangrove plant Scyphiphora hydrophyllacea Gaertn. F., a new fatty acid glucoside was isolated by column chromatography from the broth of A1, and its structure was identified as R-3-hydroxyundecanoic acid methylester-3- O-α-L- rhamnopyranoside (1) by spectroscopic methods including 1D and 2D NMR (HMQC, 1H-1H COSY and HMBC) and chemical methods. Antimicrobial assay showed compound 1 possessed modest inhibitory effect on Saphylococcus aureus and methicillin-resistant S. aureus (MRSA) using the filter paper disc agar diffusion method.
An efficient method to chiral β-hydroxy acids: Synthesis of lipid-A side chain
Nandanan,Phukan, Prodeep,Sudalai
, p. 893 - 896 (2007/10/03)
The synthesis of optically active β-hydroxy acids 5a-c is achieved in four steps from their corresponding terminal olefins 1a-c by employing Sharpless asymmetric dihydroxylation. The regioselective ring opening of chiral cyclic sulfites 3a-c with cyanide ion, constitutes the key reaction, thus producing the hydroxy nitriles 4a-c.
Asymmetric Reduction of Aliphatic Short- to Long-Chain β-Keto Acids by Use of Fermenting Bakers' Yeast
Utaka, Masanori,Watabu, Hisashi,Higashi, Hiroshi,Sakai, Takashi,Tsuboi, Sadao,Torii, Sigeru
, p. 3917 - 3921 (2007/10/02)
Eleven β-keto acids, ranging from 3-oxobutanoic to 3-oxooctanoic acids, were reduced with fermenting bakers' yeast to the corresponding optically active β-hydroxy acids, which were isolated as the methyl esters.In all cases, the (R)-hydroxy acids were obtained in >/=98percent ee, except for 3-oxobutanoic acid, which afforded the (S)-hydroxy acid in 86percent ee.Inhibition of fermentation was observed for 3-oxoundecanoic to 3-oxotetradecanoic acids, leading to no reduction.Lowering of the substrate concentration was found to be appreciably effective in avoiding inhibition.