41652-38-4Relevant articles and documents
Photoinduced Molecular Transformations. Part 153. Long-Range Intramolecular Hydroxylation of C(25) of the Cholestane Side Chain
Orito, Kazuhiko,Sato, Shinji,Suginome, Hiroshi
, p. 63 - 68 (2007/10/02)
Alkoxyl radicals generated by photolysis of the hypoiodites of 5α-cholestan-7α-yl 4-(α-hydroxyphenylmethyl)phenylacetate and 5α-cholestan-7α-yl 3-propanoate, respectively, abstracted hydrogen from C(25) of their cholestane
4-(M-benzoylphenyl)butyric acid derivatives
-
, (2008/06/13)
Novel butyric acid derivatives of the formula SPC1 Wherein X, X1, X2 and X3 are individually selected from the group consisting of hydrogen, halogen, lower alkyl of 1 to 5 carbon atoms, lower alkoxy of 1 to 5 carbon atoms, lower alkylthio of 1 to 5 carbon atoms, trifluoromethoxy, trifluoromethylthio, trifluoromethyl, OH and dilower alkylamino of 1 to 5 carbon atoms for each alkyl, R is selected from the group consisting of hydrogen, lower alkyl of 1 to 5 carbon atoms, o-carboxyphenyl, 2,3-dihydroxypropyl and -CH2 -CH - CH2 EQU1 wherein P and Q are individually lower alkyl of 1 to 5 carbon atoms, Z and X4 are individually selected from the group consisting of hydrogen and lower alkyl of 1 to 5 carbon atoms and Y is selected from the group consisting of hydrogen and --OH and the dotted line indicates the optional presence of a double bond when Y is hydrogen and when R is hydrogen or o-carboxyphenyl, the salts thereof with a non-toxic pharmaceutically acceptable mineral or organic base, which compounds have anti-inflammatory and analgesic activity and are substantially devoid of ulcerigenic activity and their preparation and novel intermediates formed therein.