426818-71-5

Basic information

• Product Name: N⁶,5'-O-ditrityladenosine-2',3'-cyclic sulfate
• Synonyms: N⁶,5'-O-ditrityladenosine-2',3'-cyclic sulfate
• CAS NO: 426818-71-5
• Molecular Weight: 813.934
• Mol File: 426818-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁶,5'-O-ditrityladenosine-2',3'-cyclic sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶,5'-O-ditrityladenosine-2',3'-cyclic sulfate(426818-71-5)
• EPA Substance Registry System: N⁶,5'-O-ditrityladenosine-2',3'-cyclic sulfate(426818-71-5)

Safety Data

• Hazardous Substances Data: 426818-71-5(Hazardous Substances Data)

Upstream product

• 31085-55-9 (2R,3R,4S,5R)-2-(6-(tritylamino)-9H-purin-9-yl)-5-((trityloxy)methyl)tetrahydrofuran-3,4-diol 

Relevant articles and documents

Fluoronucleosides, isothiocyanato C-nucleosides, and thioureylene di-C-nucleosides via cyclic sulfates

Cyclic sulfates of N- and C-nucleosides (D-ribo and D-erythro configurations, respectively) are used to prepare 3′-fluoro and 3′-azido D-Xylo N-nucleosides and L-threo C-nucleosides. The reduction of the 3′-azido C-nucleosides (furan, imidazoline-2-thione, and pyrrole derivatives) gives 3′-amino C-nucleosides, which, by reaction with thiocarbonyldiimidazole, are transformed into 3′-isothiocyanato C-nucleosides. Reaction of the 3′-amino with the 3′-isothiocyanato C-nucleosides gives thioureylene di-C-nucleosides, a type of nucleotide analogue with a nonionic bridge isosteric of the phosphate group.