437762-07-7

Basic information

• Product Name: (S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine
• Synonyms: (S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine
• CAS NO: 437762-07-7
• Molecular Weight: 291.316
• Mol File: 437762-07-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine(437762-07-7)
• EPA Substance Registry System: (S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine(437762-07-7)

Safety Data

• Hazardous Substances Data: 437762-07-7(Hazardous Substances Data)

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 17408-14-9 1-(2-(trifluoromethyl)phenyl)ethan-1-one 

Downstream Products

• 865815-09-4 (S)-1-(2-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride 
• 1332827-99-2 (S)-2,2,2-trifluoro-N-(1-(2-(trifluoromethyl)phenyl)ethyl)acetamide 
• 127733-39-5 (S)-α-(o-(trifluoromethyl)phenyl)ethylamine 
• 444643-02-1 (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine 

Relevant articles and documents

Step-efficient access to chiral primary amines

Routes to enantioenriched amines are outlined that employ reductive amination and carbanion addition methods. The strategies require either one or two reaction steps from prochiral carbonyl compounds for the synthesis of the corresponding chiral primary amines. Georg Thieme Verlag Stuttgart New York.

Highly regioselective hydrogenolysis of bis(α-methylbenzyl)amine derivatives affected by the trifluoromethyl substituent on the aromatic ring

(Matrix presented) The highly regioselective hydrogenolysis of bis(α-methylbenzyl)amine derivatives proceeded with influence not from the electronic effect but from the steric effect of the trifluoromethyl substituent on the aromatic ring to provide a practical asymmetric synthesis of trifluoromethyl-substituted α-phenylethylamines.