4383-24-8

Basic information

• Product Name: Benzenemethanamine, N-(phenylmethoxy)-
• CAS NO: 4383-24-8
• Molecular Formula: C14H15NO
• Molecular Weight: 213.279
• Mol File: 4383-24-8.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(phenylmethoxy)-(4383-24-8)
• EPA Substance Registry System: Benzenemethanamine, N-(phenylmethoxy)-(4383-24-8)

Safety Data

• Hazardous Substances Data: 4383-24-8(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 100-39-0 benzyl bromide 
• 79722-21-7 tert-butyl N-(benzyloxy)carbamate 
• 10229-60-4 Z-benzaldehyde O-benzyloxime 
• 622-33-3 N-benzyloxyamine 
• 584-08-7 potassium carbonate 
• 932-90-1 Benzaldoxime 
• 10229-59-1 O-benzyl benzaldehyde oxime eter 
• 7647-01-0 hydrogenchloride 
• 23135-14-0 N,O-dibenzyl-N-nitrosohydroxylamine 
• 857812-34-1 benzyl-benzyloxy-thiocyanato-amine 
• 1867-23-8 N-benzyloxy-N-benzylcarbamic acid ethyl ester 
• 17146-21-3 O-(benzyl)benzaldoxime 

Downstream Products

• 15256-53-8 N-(4-Carboxy-butyryl)-O,N-bis-benzyl-hydroxylamin 
• 5555-80-6 N-Benzyl-N-benzyloxy-carbamidsaeure-isobutylester 
• 100-44-7 benzyl chloride 
• 622-30-0 N-benzyl hydroxylalmine 
• 120823-13-4 α-(4-Benzyloxyphenyl)-N,O-dibenzyl acetohydroxamate 
• 15256-52-7 N-Chloracetyl-O,N-bis-benzyl-hydroxylamin 
• 5553-63-9 N-Benzyloxy-N-benzyl-N'-acetyl-harnstoff 
• 15258-18-1 N-Benzyl-N-benzyloxy-carbamidsaeure-(3-methoxy-propylester) 
• 130185-10-3 (3S,4S)-4-<(S)-1-(N-benzyl-N-benzyloxycarbamoyloxy)ethyl>-3-<(R)-1-tetrahydropyran-2-yloxyethyl>-2-azetidinone 
• 5553-72-0 N-Octanoyl-O,N-bis-benzyl-hydroxylamin 
• 5555-82-8 N-(phenylmethoxy)-N-bnzylphenoxycarboxamide 
• 5999-36-0 N-Isobutyryl-O,N-bis-benzyl-hydroxylamin 
• 5553-71-9 N-Propionyl-O,N-bis-benzyl-hydroxylamin 
• 5555-81-7 C₂₁H₂₇NO₃ 

Relevant articles and documents

Metal-free, redox-neutral, site-selective access to heteroarylamine via direct radical?radical cross-coupling powered by visible light photocatalysis

Transition-metal-catalyzed C?N bond-forming reactions have emerged as fundamental and powerful tools to construct arylamines, a common structure found in drug agents, natural products, and fine chemicals. Reported herein is an alternative access to heteroarylamine via radical?radical cross-coupling pathway, powered by visible light catalysis without any aid of external oxidant and reductant. Only by visible light irradiation of a photocatalyst, such as a metal-free photocatalyst, does the cascade single-electron transfer event for amines and heteroaryl nitriles occur, demonstrated by steady-state and transient spectroscopic studies, resulting in an amine radical cation and aryl radical anion in situ for C?N bond formation. The metal-free and redox economic nature, high efficiency, and site-selectivity of C?N cross-coupling of a range of available amines, hydroxylamines, and hydrazines with heteroaryl nitriles make this protocol promising in both academic and industrial settings.

Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid

Histone deacetylase (HDAC) proteins have emerged as targets for anti-cancer therapeutics, with several inhibitors used in the clinic, including suberoylanilide hydroxamic acid (SAHA, vorinostat). Because SAHA and many other inhibitors target all or most o

Phytotoxic effects of selected N-benzyl-benzoylhydroxamic acid metallo-oxygenase inhibitors: Investigation into mechanism of action

Treatment of Arabidopsis thaliana with 100 μM hydroxamic acids F1 and F2, found previously to inhibit carotenoid cleavage dioxygenase enzyme CCD1, was found to cause chlorophyll bleaching and phytotoxicity. A further set of hydroxamic acid analogues was synthesised, and these compounds were found to be phytotoxic towards A. thaliana at 16-400 μM, and to show some phytoxicity towards broad-leaved weeds C. album and S. media at 100 μM. Compound F1 was found to inhibit p-hydroxy-phenylpyruvate dioxygenase (HPPD), a known herbicide target (IC50 30 μM), but compounds F5 and F8 showed no inhibition of HPPD, despite F8 showing higher levels of phytotoxicity. Plants grown in the presence of F1 or F5 that were treated with 50 μM homogentisic acid showed partial recovery of growth, indicating some inhibition of HPPD in planta. These are the first hydroxamic acid inhibitors reported for HPPD, but the results indicate that inhibition of HPPD is only partly responsible for the observed phytotoxicity, and that another unknown metalloenzyme is also targeted by these compounds.