79722-21-7Relevant articles and documents
Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity
Pflieger, Marc,S?nnichsen, Melf,Horstick-Muche, Nadine,Yang, Jing,Schliehe-Diecks, Julian,Sch?ler, Andrea,Borkhardt, Arndt,Hamacher, Alexandra,Kassack, Matthias U.,Hansen, Finn K.,Bhatia, Sanil,Kurz, Thomas
, p. 1798 - 1803 (2021)
The acetylome is important for maintaining the homeostasis of cells. Abnormal changes can result in the pathogenesis of immunological or neurological diseases, and degeneration can promote the manifestation of cancer. In particular, pharmacological interv
Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators
Albanese, Valentina,Baldi, Andrea,Fritsky, Igor O.,Guerrini, Remo,Gumienna-Kontecka, Elzbieta,Illuminati, Davide,Mular, Andrzej,Ostrowska, Ma?gorzata,Pacifico, Salvatore,Piasta, Karolina,Remelli, Maurizio,Toporivska, Yuliya
, p. 13332 - 13347 (2021/09/11)
Increasing attention has been recently devoted to 89Zr(IV) and 68Ga(III) radionuclides, due to their favorable decay characteristics for positron emission tomography (PET). In the present paper, a deep investigation is presented on Ga(III) and Zr(IV) comp
NOVEL ALKENYL AND BETA-SUBSTITUTED PHOSPHONATES AS ANTIMICROBIAL AGENTS
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Paragraph 0088; 0092; 0116; 0162, (2019/01/17)
The present disclosure relates to novel compounds, pharmaceutical compositions, and methods for treating or preventing microbial infection caused by parasites or bacteria, such as Plasmodium falciparum or related Plasmodium parasite species and Mycobacterium tuberculosis or related Mycobacterium bacteria species. The compounds are α,β-unsaturated analogs of fosmidomycin and can inhibit deoxyxylulose phosphate reductoisomerase (Dxr) in many microbes, such as P. falciparum.